Applications of Raman Spectroscopy in Breast Cancer Surgery: A SciX Interview with Ioan Notingher, Part 2

The SciX 2024 Conference will provide the opportunity for scientists, academics, industry professionals, and researchers to share their latest research and new products with the analytical chemistry and spectroscopy community at large. Taking place in Raleigh, North Carolina, the SciX Conference will serve as an opportunity for attendees to gather in one space and network with one another.

In part 1 of our conversation with Ioan Notingher, a physicist at the University of Nottingham, he discussed the background of his talk that he plans on delivering during the SciX Conference (1). Recently, Notingher and his team explored how autofluorescence (AF) imaging, when used in conjunction with Raman spectroscopy, can assist in the intra-operative assessment of sentinel lymph nodes (SLNs) in breast cancer surgery (2). A SLN biopsy is a common procedure for patients afflicted with breast cancer (2).

Notingher currently leads the Biophotonics Group. He graduated from Babes-Bolyai University in Romania and completed his PhD at London South Bank University, followed by postdoctoral research at Imperial College London and Edinburgh University (3). Appointed as a lecturer at Nottingham in 2006, his research focuses on optical microscopy and spectroscopy techniques for label-free molecular imaging of biomaterials, cells, and tissues (3). This year, Notingher will be receiving the William F. Meggers Award at the SciX Conference (3).

We continue our discussion with Notingher about his research in part 2. In particular, we focus on AF-Raman technology, and how this technology is improving clinical analysis.

In part 2 of our conversation with Notingher, he answers the following questions:

• What are the next steps for developing the AF-Raman technology, combining autofluorescence (AF) imaging with Raman spectroscopy, and what are your expectations for its practical clinical adoption soon?
• What are the advantages of using Raman spectroscopy for non-invasive, real-time analysis of stem cell differentiation compared to traditional techniques?

To view the rest of our coverage of the upcoming SciX 2024 Conference, click here: https://www.spectroscopyonline.com/conferences/scix

References

1. Wetzel, W. Applications of Raman Spectroscopy in Breast Cancer Surgery: A SciX Interview with Ioan Notingher, Part 1. Spectroscopy. Available at: https://www.spectroscopyonline.com/view/applications-of-raman-spectroscopy-in-breast-cancer-surgery-a-scix-interview-with-ioan-notingher-part-1 (accessed 2024-10-04).
2. Barkur, S.; Boiter, R. A.; Mihai, R.; et al. Intraoperative Spectroscopic Evaluation of Sentinel Lymph Nodes in Breast Cancer Surgery. Breast Cancer Res. Treat. 2024, 207 (1), 223–232. DOI: 10.1007/s10549-024-07349-z
3. Chasse, J. Intraoperative Spectroscopic Evaluation of Sentinel Lymph Nodes in Breast Cancer Surgery: An Interview with William F. Meggers Award Winner Ioan Notingher. Spectroscopy. Available at: https://www.spectroscopyonline.com/view/intraoperative-spectroscopic-evaluation-of-sentinel-lymph-nodes-in-breast-cancer-surgery-an-interview-with-william-f-meggers-award-winner-ioan-notingher (accessed 2024-10-04).