Molecular Spectroscopy

Researchers from Université de Montréal have demonstrated that a new handheld Raman spectroscopy device, the UltraProbe, can accurately and rapidly detect retroperitoneal soft tissue sarcomas during surgery, offering real-time tissue analysis that could improve surgical outcomes.

A recent study demonstrated that portable Raman spectroscopy, combined with advanced statistical modeling, offers a reliable, non-destructive method for monitoring nitrate levels in greenhouse-grown spinach.

Top articles published this week include a feature article about big pharma’s investments in U.S.-based manufacturing, an article about the 2025 Emerging Leader in Molecular Spectroscopy Lingyan Shi, and some news items detailing the winners of the Coblentz Society’s student awards.

This study presents a new system that enables the precise detection of glucose, choline, and lactate without traditional labels or antibodies.

A recent study unveiled a new adaptive Raman spectroscopy and transformer-based model for fast, high-accuracy microbial classification.

A compilation of articles that explore the role of Raman spectroscopy in cancer research is presented.

Researchers at Heilongjiang University have developed a rapid and accurate method for detecting sweeteners in food using Raman spectroscopy combined with a Random Forest machine learning algorithm, offering a powerful tool for improving food safety.

A recent study reports high-purity blue emission and thermal stability in novel lanthanum (III) complex synthesized via low-energy precipitation method.

A recent study developed new photoacoustic probes to better visualize oxidative stress during acute liver injury.

Researchers from the Institute of Agrifood Research and Technology (IRTA) in Catalunya, Spain used fluorescence and Raman spectroscopy to explore complex tissue changes behind wooden breast myopathy in chickens.

In an announcement on June 12, Rigaku Analytical Devices, which is a division of Rigaku Holdings Corporation headquartered in Akishima, Tokyo, announced the launch of its Icon series of 1064-nm Raman analyzers, its fourth-generation of the instrument.

Researchers use EC-SERS to reveal the first detailed structural study of hU-II peptide in aqueous solution, paving the way for new drug development.

Researchers at McGill University have developed a fast, eco-friendly method using portable Raman spectroscopy and deep learning to accurately assess the antioxidant content of maple syrup on-site.

Researchers at Guangdong University of Technology have developed a fast, non-destructive Raman spectroscopy method to accurately detect active ingredients in complex drug formulations.

A recent study published in the Journal of Archaeological Science: Reports reveals that a multi-headed snake motif at Argentina's La Candelaria rock shelter was created through multiple painting events over time.

The 78th International Symposium on Molecular Spectroscopy (ISMS) is set to take place this year from June 23rd to 27th, 2025. Here is what attendees can expect.

Researchers at Qiqihar Medical University have developed a dual-channel fluorescent probe, PYL-NBD, that enables highly sensitive, rapid, and selective detection of biothiols in food, pharmaceuticals, and living organisms.

A new study published in Spectrochimica Acta Part A by Dominik Heger and colleagues at Masaryk University reveals that phenol's photophysical properties change significantly when frozen, potentially enabling its breakdown by sunlight in icy environments.

A recent study demonstrated the utility of Raman spectroscopy and machine learning (ML) algorithms to classify plastic types found in waste of electric and electronic equipment (WEEE) streams.

A recent study by Southeast University researchers presented a cost-effective, high-accuracy solution for pharmaceutical quality control.

Researchers in China have developed a rapid, non-destructive Raman spectroscopy method that accurately detects active components in complex drug formulations by combining advanced algorithms to eliminate noise and fluorescence interference.

Tianjin University researchers develop an advanced AI model to enhance food safety.

A compilation of some of the top articles from our Molecular Spectroscopy Workbench column is presented.

In this Icons of Spectroscopy column, Executive Editor Jerome Workman Jr. delves into Part II of the Raman Effect, discovered by C. V. Raman, a physicist whose major contributions to vibrational spectroscopy have helped shape the field and advance one of the most important quantum-based spectroscopy tools of recent generations.

HORIBA has released three new products including tools for Raman screening, advanced molecular fingerprinting, and atomic fingerprinting. Two of these new tools will be highlighted during Pittcon.

In this column, I describe what I believe may be the origin of this fluorescence emission and support my conjecture with some measurements of polycyclic aromatic hydrocarbons (PAHs). Understanding the origin of these interfering backgrounds may enable you to design experiments with less interference, avoid the laser illuminations that make things worse, or both.

Last year, we released a content series titled “Advancing Agriculture for Future Generations.” Here, we compile some of the latest studies in this space.

A recent study out of China explored using a new continuous solid-phase extraction spectroscopy (CSPES) device to monitor water quality.

To improve the robustness and accuracy of logistic regression identification method, a new Raman spectroscopy identification method was proposed that combines a distributionally robust optimization technique and fused lasso technique with logistic regression. Then, Raman spectroscopy was used to analyze two types of dairy products that were collected for anti-jamming identification testing to verify the effectiveness of the new method.