MilliporeSigma: Ultrapure Water to Assess Trace Element Impurities in Pharmaceuticals

Discover why Specac is your trusted partner for process analytical technology, especially for challenging liquid and gas samples. Our robust solutions ensure reliable process control, enhancing safety, reducing waste, and supporting the Green transition in industrial chemistry.

The optimal pathlength for an on-line FT-NIR process measurement needs to be determined by experimentation. Here we demonstrate the feasibility of measuring water in acetone by NIR spectroscopy at various pathlengths using an adjustable Spyder™ process flow cell, as a prelude to full-scale implementation of NIR process analysis on a production line.

Specac latest innovation - the Spyder™ is your go-to spectroscopic liquid flow cell, perfect for labs and small-scale pilot plants. Just connect it to a near-infrared process analyzer with fiber optic cables, and you’ll unlock seamless analysis of liquid products as they flow through your continuous chemical process.

This work demonstrates the effective elemental impurities analysis of pharmaceuticals per USP <232>/<233> harmonized with ICH Q3D using PerkinElmer's NexION® 1100 ICP-MS.

Because blanks should be blank. Learn how reagent water quality can impact trace element analyses in the pharmaceutical industry.

Compositional Depth Profile (CDP) using the LECO GDS950 rapidly provides analysis of various galvanized coatings on steel.