Optimizing Tissue Preparation and Storage for Analysis of Polyunsaturated Fatty Acids Using Agilent’s FT-IR Imaging Systems
Mammals require dietary-based polyunsaturated fatty acids (PUFA) such as docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and arachidonic acid (AA) for many biological processes, including normal functioning of the retina and brain. Fourier transform infrared (FTIR) imaging with high spatial resolution is a suitable tool to investigate the PUFA distribution in tissue sections from animal models of disease, providing comprehensive information of the biochemical components on the subcellular scale.
Combining SERS and Machine Learning to Advance Single-Cell Analysis
December 13th 2024Researchers from Stanford University have combined surface-enhanced Raman spectroscopy (SERS) with machine learning (ML) to enable rapid, precise single-cell analysis, offering potentially transformative applications in diagnostics and personalized medicine.
Using Raman Spectroscopy and Surface-enhanced Raman Spectroscopy to Detect Cholesterol Disorders
November 25th 2024Researchers have developed a highly sensitive method using Raman and surface-enhanced Raman spectroscopy (SERS) with gold nanoparticles to accurately quantify intracellular cholesterol.
Best of the Week: Cancer Biomarkers and Screening, Raman for Hematology Diagnostics
November 8th 2024Top articles published this week include an interview with Landulfo Silveira Jr., an article about using Raman spectroscopy in hematology, and a recap of a recent study that used infrared (IR) spectroscopy to screen for cancer.
