Analytical Tools for the Characterization of Biopharmaceuticals: Mass Spectrometric Detection

Researchers at Nagoya University and RIKEN have developed a novel computational method to enhance the resolution of high-speed atomic force microscopy (HS-AFM) images for studying protein conformational transitions. The algorithm, normal mode flexible fitting-atomic force microscopy (NMFF-AFM), leverages normal-mode analysis to derive precise molecular models, potentially transforming the understanding of biomolecular dynamics.

Joseph P. Smith, Director of Process R&D Enabling Technologies at Merck has been awarded the 2024 Emerging Leader in Molecular Spectroscopy Award, recognizing his significant contributions to the advancement of molecular spectroscopy in the pharmaceutical industry.

This review highlights very recent advancements in several key spectroscopic methods, including atomic, vibrational, molecular, electronic, and diffraction techniques.

Scientists from the Czech Republic recently created new practices to study different Tröger’s base isomers.

Henan University scientists recently developed a new deep learning-based prediction model for classifying nonclassical secreted proteins.

Howard University scientists recently analyzed tryptophan (Trp) networks and conditions under ultraviolet superradiance.