Spectroscopy-06-01-2009
Statistics and Chemometrics for Clinical Data Reporting, Part I
June 1st 2009This article describes the application of chemometric methods and statistics for reporting clinical quantitative measurement methods. The equations and terminology are consistent with the Clinical and Laboratory Standards Institute (CLSI) guidelines. These chemometric and statistical methods describe the accuracy and precision of a test method compared to a reference method for a single analyte determination. Part I will introduce these concepts and Part II will discuss the statistical underpinnings in greater detail.
Market Profile: Raman-Enabled FT-IR
June 1st 2009Infrared (IR) spectroscopy and Raman spectroscopy are very complementary methods. The strongest demand tends to come from applications that require analytical information from a potentially broad range of compounds and functional groups. The global market for combined Raman and FT-IR accounts for a small but growing percentage of both the broader IR and Raman spectroscopy markets.
Understanding and Interpreting the New GAMP 5 Software Categories
June 1st 2009The GAMP (Good Automated Manufacturing Practice) guide version 5 was released in March 2008 and one of the changes was that the classification of software was revised - again. This column will look at what the changes mean for the laboratory and whether all of these should be implemented.
![Spectral Studies on the Interaction of [Ru(bpy)2(BTIP)]+2 with DNA and Determination of Nucleic Acids at Nanogram Levels](/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fspectroscopy%2F45c59ac7d3d339f0f04bc7f7efefcbda0c51c9c3-120x80.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 "Spectral Studies on the Interaction of [Ru(bpy)2(BTIP)]+2 with DNA and Determination of Nucleic Acids at Nanogram Levels")
Current Status of Standoff LIBS Security Applications at the United States Army Research Laboratory
June 1st 2009The United States Army Research Laboratory (ARL) has been applying standoff laser-induced breakdown spectroscopy (LIBS) to hazardous material detection and determination. We describe several standoff systems that have been developed by ARL and provide a brief overview of standoff LIBS progress at ARL. We also present some current standoff LIBS results from explosive residues on organic substrates and biomaterials from different growth media. These new preliminary results demonstrate that standoff LIBS has the potential to discriminate hazardous materials in more complex backgrounds.
