Hydrogen–Deuterium Exchange Mass Spectrometry
July 1st 2013A detailed look at H–D exchange mass spectrometry including the history of the technique, the exchange process itself, and how the current state of the art provides insights into complex protein structures and their dynamics.
Femtosecond Pulse Shaping Enables Rapid Two-Dimensional Infrared Spectroscopy
July 1st 2013Here, Martin Zanni explains two dimensional (2D) infrared spectroscopy, the role of lasers, and current applications, such as studying the kinetics of protein aggregation in diabetes.