Product Resources
Product Resources
Ion-trap mass spectrometer
The Thermo Scientific LTQ XL linear ion-trap mass spectrometer is equipped with electron transfer dissociation (ETD), which reportedly provides advantages for protein and peptide characterization, posttranslational modification analysis, and top-down or middle-down sequencing of proteins and peptides. According to the company, the ETD feature allows researchers to conduct rapid, alternating collisionally induced dissociation and ETD scanning throughout the LC–MS analysis of complex samples. Thermo Fisher Scientific, Inc., Waltham, MA;
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TOF MS
Hitachi's NanoFrontier with TOF MS is designed for preserving posttranslational modifications (PTM) with electron capture dissociation (ECD), which allows definitive PTM site and type determinations. According to the company, the product provides high-throughput intelligent control of combined ECD and CID scans for interrogation of modified proteins. Hitachi High Technologies America, San Jose, CA;
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GC–MS system
PerkinElmer's Clarus 560 D GC–MS system is designed for lower-volume laboratories' routine application needs. According to the company, the system offers increased productivity through state-of-the-art electronics, the fastest scanning rates to yield the most accurate data, the widest mass range, and the latest in reporting capabilities for easy environmental compliance. The compact system also includes a GC autosampler, a touch-screen interface, and dual channels for additional application work. Perkin Elmer, Inc., Wellesley, MA;
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GC–MS system
Agilent's model 5975C GC–MS system includes a trace ion detection feature that is designed to reduce chemical noise and improve peak shape and spectral fidelity. The system reportedly offers a hydrogen carrier gas specification and a high-temperature ion source that operates at temperatures as high as 350 °C. Agilent Technologies Inc., Wilmington, DE;
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Ion mobility spectrometry
The IONSCAN-LS by Smiths Detection is designed to detect and quantitate trace analytes using ion mobility spectrometry with two sample introduction methods: thermal desorption from a filter and high-performance injection. According to the company, the product can analyze samples over a concentration range of about three orders of magnitude. Smiths Detection, Danbury, CT;
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Mass spectrometer
Bruker Daltonics announces its ultraflex III smartbeam MALDI-TOF-TOF mass spectrometer, optimized for MALDI molecular imaging. The product is designed to produce a laser focus size of 10–80 μm, with adjustable repetition rates from 1 Hz to 200 Hz. Bruker Optics, Billerica, MA;
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MS system
The Waters Synapt High Definition MS (HDMS) system is designed for researchers working at the limits of conventional MS and who need to further characterize and define complex samples. The system reportedly uses an ion-mobility-based measurement and software to analyze sample ions differentiated by size and shape. According to the company, this additional dimension of separations fidelity leads to improved specificity and sample definition. Waters Corporation, Milford, MA;
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LC–MS-MS system
Thermo Scientific's EQuan environmental quantitation system coupled with the company's TSQ Quantum triple-quadrupole MS system is designed for the analysis of pesticides, herbicides, antimicrobials, and other pharmaceuticals in environmental and drinking water samples. The quantitation system's on-line sample enrichment technique reportedly reduces analysis time from days to minutes, while maintaining sensitivity and specificity. Thermo Fisher Scientific, San Jose, CA;
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Ion mobility spectrometer
The TSI 3980C MacroIMS ion mobility spectrometer is designed for fast separation of macromoles. According to the company, the instrument's software allows overlay of spectra, raw data smoothing, and molecular weight-based controls and statistics. TSI Incorporated, Shoreview, MN;
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High-voltage resistors
The KOBRA precision metal oxide high-voltage resistors from ITT Power Solutions are available in power, cylindrical, flat, ring, and custom versions. According to the company, many resistors are available lead-free and RoHS compliant. ITT Power Solutions, West Springfield, MA;
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HPLC column
Dionex's ProPac HIC-10 silica-based high-capacity HPLC column is designed for the separation of proteins and peptides by hydrophobic interaction chromatography. According to the company, the column has been used for applications ranging from the separation of serum proteins, human skeletal muscle total protein, and snake venom proteins to pancreatin and monoclonal antibodies. The column's stationary phase is based on 5-mm ultrahigh-purity spherical silica gel particles, with 300-Å pores. Dionex Corporation, Sunnyvale, CA;
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GC-MS system
Shimadzu's QP-2010 Plus GC–MS system is designed for rapid analysis of difficult samples, the determination of trace components, and the characterization of complex organic mixtures. The system reportedly provides a 1.5–1090 m/z mass range as well as a 100–300 °C ion source temperature range. Shimadzu Scientific Instruments, Inc., Columbia, MD;
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Portable GC–MS system
The Guardian-7 portable GC–MS system by Torion features a low-thermal-mass capillary gas chromatograph with ballistic temperature programming and a miniature toroidal ion trap mass spectrometer with a mass range of 50 to >500 Da. According to the company, the system is totally self-contained, weighs less than 25 lb, is battery operated, and is hand-portable. Torion Technologies Inc., Pleasant Grove, UT;
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HPLC columns for MS
The silica and phenyl phases of Supelco's Ascentis HPLC columns are designed for aqueous normal-phase or HILIC applications. The silica phase is available in a wide variety of dimensions and is scalable from microbore to preparative dimensions. The phenyl phase reportedly provides unique selectivity as well as minimal MS bleed, making it suitable for LC–MS applications. Supelco, Bellefonte, PA;
www.sigma-aldrich.com/supelco/
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Power supply
Spellman High Voltage Electronics Corporation introduces its model VS100 high-voltage power supply, designed for precision electron beam applications such as semiconductor nanolithography, microoptics, and development mask work. According to the company, the product features ultra low ripple (less than 75 mV p-p, for 100 kV at 100 μA), high stability, and excellent regulation parameters. Spellman High Voltage, Hauppage, NY;
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Ion sources
Prosolia's Omni Spray Ion sources are a series of ionization sources based on desorption electrospray ionization (DESI). DESI is a simple, sensitive, gentle, and versatile ionization method that allows for the direct and rapid sampling of surfaces without any sample preparation and under ambient temperature and pressure conditions. According to the company, with this source, scientists are able to analyze both large and small molecules from a variety of surfaces. Prosolia, Inc., Indianapolis, IN;
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