Mass Spectrometry

A new quadupole ICP-MS instrument has been designed to improve the sensitivity of this elemental analysis technique.

The author discusses how the physical realm of the atmospheric ionization source -- materials, gas, and heat dynamics -- and manipulating the ionization modes themselves perhaps are the current forefront of technological innovation.

The authors discuss how the dynamics associated with laser ablation solid sampling systems ensures greater analytical precision and accuracy for ICP-MS/OES trace element analysis.

Inductively coupled plasma-mass spectrometry (ICP-MS) is a powerful technique for elemental and isotopic analysis that combines the efficiency and ease of use of the ICP component with the sensitivity and selectivity of MS.

The fourth installment in the continuing series concentrates on issues that are amenable to mathematical analysis.

Careful consideration of the dynamics associated with laser ablation solid sampling systems ensures greater analytical precision and accuracy for ICP-MS/OES element analysis.

Editorial index for articles published in 2003.

This series about derivatives in spectroscopy continues with a discussion about some of the practical aspects of computing the derivative.

This article is the third installment in a series about a novel spectrofluorometric method that allow for in vivo observation of the division of chlorplast populations in leaves of Arabidopsis thalania.

A diagrammatic view of the concept of detection limits is presented that effectively shows its relationship to the reproducibility of measurements on the blank.

This article examines temperature-induced effects on surface-enhanced Raman scattering of PHBA and MHBA adsorbed on silver colloidal particles.

The author discusses several mathematical processing methods for handling, assessing, and studying groups containing multiple spectra. The processing techniques feature standard mathematical tools that are used to study a series of numerical results.

The author discusses photoelectron spectroscopy theory and describes radiation sources used in the technique.

Rapid near-infrared spectroscopy measurement near the process line of lab applications may speed up the process.

Vibrational and fluorescence spectroscopy, laser light-scattering techniques, and other optics-based approaches are gaining momentum in the quest for early detection and more effective treatment of cancer.

This article discusses direct real-time monitoring of chemical reactions, an important tool in industrial processes in industries such as chemical, biotechnology, food, and pharmaceutical.

The author describes applying validation principles originally designed for lab instruments to process instruments.

The authors continue their series on derivatives in spectroscopy.

The author previews the 13th annual Winter Plasma Spectrochemistry conference.

Near-infrared spectroscopy moves into warehouses to check incoming drug substances, excipients, and packaging materials, and onto the production floor to monitor characteristics such as blend uniformity, moisture content, and dissolution rate.

The author discusses the process analytical technologies initiative and its effect on spectroscopy.

Infrared technology was used as a method for rapid detection of potential Severe Acute Respiratory Syndrome.

Trace-level detection of explosives using spectrometric techniques.

The author discusses how to identify some of the performance qualification tests to apply to spectrometry software, how to write the test procedures and instructions, and how to execute the actual testing.

This article provides a brief overview of some of the latest spectroscopy-related equipment and supplies scheduled to be introduced at the 2003 Denver X-ray Conference at the Denver Marriott Tech Center Hotel in Denver, Colorado, August 4?8, 2003.

The x-ray energy spectrum provides rapid identification of mineral samples.

Oregon Health and Science University (OHSU, Portland) has proposed a research and academic program in chemical biology in which chemists and biologists work next to each other, in the same facility, on drug discovery projects.

This first installment in a series about challenges and pitfalls in interpreting data from hyphenated techniques explores general concepts in initial approaches.

The author discusses an alternative to filament sources when working with electron ionization.

The authors discuss the use of serial coulometric flow cells coupled online with electrospray ionization mass spectrometry in predictive assays for absorption, distribution, metabolism, excretion, toxicity (ADME/Tox), and stability implemented at early stages of drug discovery.