How Using Raman Spectroscopy and SIMPLISMA Can Accelerate the Study of Polymorphs: A Case Study Using Carbamazepine (PDF)

Article

Special Issues

Spectroscopy SupplementsSpecial Issues-06-02-2004
Volume 0
Issue 0

The authors show how a multivariate curve resolution algorithm, called SIMPLe-to-use Interactive Self-modeling Mixture Analysis (SIMPLISMA), can facilitate the quantitative and qualitative analysis of difficult samples, and apply the algorithm to a technically challenging Raman spectra series for carbamazepine polymorphs.

To view a PDF of this article from the Spectroscopy Online archives, click this link.

Articles in this issue
Case Studies in the Application of Raman Microscopy (PDF)
Powerful Partners Provide Complete Analytical Solutions (PDF)
Raman Microscopy as a Valuable Tool for Failure Analysis (PDF)
Identifying Macromolecules (PDF)
A New Era in Affordable Raman Spectroscopy (PDF)
How Using Raman Spectroscopy and SIMPLISMA Can Accelerate the Study of Polymorphs: A Case Study Using Carbamazepine (PDF)
Raman Spectroscopy for Homeland Defense Applications (PDF)
Recent Videos
The country Sierra Leone is in West Africa, and benefits from a tropical Atlantic coastline. Its bordered by Guinea and Liberia. The Capital is Freetown, and you can head to the beach in Sierra Leone. | Image Credit: © KALADA - stock.adobe.com.
Modern video camera recording tv studio interview blurred background mass media technology concept | Image Credit: © Studios - stock.adobe.com.
Modern video camera recording tv studio interview blurred background mass media technology concept | Image Credit: © Studios - stock.adobe.com.
Related Content
Mars rover exploring rocky Martian landscape under starry night © SerPak-chronicles-stock.adobe.com

New Spectroscopic Evidence of Hydrothermal Activity on Mars Revealed by Perseverance Rover

Jerome Workman, Jr.
April 2nd 2025
Article

Using LIBS, infrared, and Raman spectroscopic techniques scientists detect quartz and hydrated silica, hinting at past Martian water activity and potential biosignatures

twitter-822313-1408532797013.jpg

Improving Raman Probes for Cosmetic and Medical Research

September 6th 2013
Podcast

An interview with Paul Pudney, a winner of the William F. Meggers Award.

Jezero Crater on the planet Mars © mkarco and NASA-chronicles-stock.adobe.com

SuperCam Raman Spectroscopy Unlocks Jezero Crater’s Geological Secrets

Jerome Workman, Jr.
March 31st 2025
Article

Scientists detail the first 1,000 sols of spectroscopic mineral detections on Mars

twitter-819466-1408538616786.jpg

Combining Spectroscopic and Chromatographic Techniques

August 1st 2013
Podcast

An interview with Charles Wilkins, the winner of the 2013 American Chemical Society Division of Analytical Chemistry Award in Chemical Instrumentation, sponsored by the Dow Chemical Company.

Professor Yukihiro Ozaki, Recipient of the 2025 Ellis R. Lippincott Award

A Life of Spectroscopic Exploration: An Interview with Professor Yukihiro Ozaki, Recipient of the 2025 Ellis R. Lippincott Award

Jerome Workman, Jr.
March 24th 2025
Article
Tomas B. Hirschfeld

Tomas Hirschfeld: Prolific Research Chemist, Mentor, Inventor, and Futurist

Jerome Workman, Jr.
March 19th 2025
Article

In this "Icons of Spectroscopy" column, executive editor Jerome Workman Jr. details how Tomas B. Hirschfeld has made many significant contributions to vibrational spectroscopy and has inspired and mentored many leading scientists of the past several decades.