Handheld Raman spectrometers can distinguish raw materials through transparent and opaque packaging containers. This application note demonstrates the use of the handheld Agilent Vaya Raman raw material identity verification system based on spatially offset Raman spectroscopy (SORS) for chemical ID verification and testing of mRNA lipid nanoparticle (LNP) components through transparent glass and white opaque polyethylene containers.