Agilent

Thermal melt (Tm) analysis using rapid, precise temperature-dependent UV-Vis absorbance measurements

Fast and precise thermal melt (Tm ) measurements using the Agilent Cary 3500 UV-Vis spectrophotometer

Accelerating research into oligonucleotides and proteins with the Agilent Cary 3500 UV-Vis

Benefits of the Agilent Cary 3500 UV-Vis spectrophotometer with a Peltier temperature-controlled multicell in protein therapeutic research

Webinar Date/Time: Tue, Dec 3, 2024 11:00 AM EST

Webinar Date/Time: Session 1: Tues, Dec 5, 2024, at 12:00 PM BST | 1:00 PM CET Session 2: Tues, Dec 5, 2024, at 11:00 AM PST | 2:00 PM EST | 7:00 PM GMT Session 3: Wed, Dec 6, 2024, at 9:30 AM IST | 12:00 PM SGT | 1:00 PM JST | 3:00 PM AEDT

The Agilent Vaya Raman system is a handheld spectrometer capable of identifying raw materials through transparent and opaque containers. This white paper discusses some of the benefits of deploying a Vaya system in a pharmaceutical warehouse, to simplify and accelerate the ID verification of raw materials at receipt.

This study demonstrates the through-opaque-container analysis capability of the Agilent Vaya handheld Raman spectrometer by performing measurements on a range of common excipients and active ingredients within blue barrels.

Webinar Date/Time: Thursday, September 26, 2024 Morning Session: 10:00 AM EDT | 7:00 AM PDT | 3:00 PM BST | 4:00 PM CEST Afternoon Sesson: 12:30 PM EDT | 9:30 AM PDT | 5:30 PM BST | 6:30 PM CEST

Webinar Date/Time: Thursday, October 10, 2024 at 10 AM BST | 11 AM CEST

Webinar Date/Time: Thursday, September 12th, 2024 English Session: 10:00 AM BST | 11:00 AM CEST French Session: 10:00 AM BST | 11:00 AM CEST

This study demonstrates the through-opaque-container analysis capability of the Agilent Vaya handheld Raman spectrometer by performing measurements on a range of common excipients and active ingredients within blue barrels. Spatially offset Raman spectroscopy (SORS) is the unique Agilent technology that is the basis of the unique Vaya container subtraction algorithm. This technology can optimize the spectra to provide the clearest signature of contents with the minimum amount of container interference. Verification of raw materials directly through plastic barrels provides efficient raw material identification (RMID) workflows in the warehouse without the need for specialized personnel or controlled sampling environments.

Handheld Raman spectrometers can distinguish raw materials through transparent and opaque packaging containers. This application note demonstrates the use of the handheld Agilent Vaya Raman raw material identity verification system based on spatially offset Raman spectroscopy (SORS) for chemical ID verification and testing of mRNA lipid nanoparticle (LNP) components through transparent glass and white opaque polyethylene containers.

Over 85% of scientific organizations have incorporated environmental sustainability into their long term goals and commitments. Agilent helps scientists reach their sustainability goals without compromising results or productivity, with products developed with the environment in mind. The Accountability, Consistency, and Transparency Label (ACT label) helps to communicate the environmental impact of manufacturing, operation, and disposal of scientific products and packaging, helping scientists make green equipment decisions. Agilent Vaya handheld Raman spectrometers are ACT Label certified and enable zero-waste workflows, offering a green choice for raw material identification workflows.

Magnesium, calcium, or zinc stearates are commonly used in pharmaceutical drug manufacturing. While these metal stearates exhibit similar chemical properties, they are not necessarily interchangeable in manufacturing processes. It is critical therefore that they are identified and differentiated at receipt in the warehouse to avoid process disruptions. Accurately differentiating stearate analogs at receipt by Raman spectroscopy has historically been challenging. Given the similarities of the spectra of the compounds, sophisticated chemometric software is often needed to build stearate models that are then used to identify them. This study shows that the Agilent Vaya handheld Raman spectrometer with Spatially Offset Raman Spectroscopy (SORS) can identify metal stearates in their original primary packaging, without the need for complex chemometric software packages. The handheld Vaya Raman enables the selective verification of stearates using a two-criteria decision algorithm combined with the "Analogous Sample" software feature.

This Agilent application note details the use of a Cary 5000 UV-Vis-NIR spectrophotometer with a universal measurement accessory for the optical characterization and reverse-engineering of thin films. It emphasizes the importance of multi-angle spectral photometric data in assessing the optical parameters of thin films, which is crucial for quality control in manufacturing processes.

This Agilent application note discusses the Cary 7000 UMS, a system for mapping coated wafers using UV-Vis spectral reflection and transmission measurements. It introduces a new autosampler for automated, high-resolution mapping of large samples and demonstrates its utility with a zinc tin oxide layer on a sapphire substrate.

The Agilent Cary 5000 UV-Vis-NIR spectrophotometer, equipped with a Praying Mantis diffuse reflectance accessory, is ideal for analyzing catalyst powders. It provides valuable insights into chemical transformations across a broad temperature range, from 20 to 250 °C, enhancing the understanding of catalytic processes.

Webinar Date/Time: Wednesday, June 26th, 2024 at 8am PDT | 11am EDT | 4pm BST | 5pm CEST

The Agilent Advanced Dilution System 2 (ADS 2) is a new two-syringe autodilution system for Agilent ICP-MS instruments that can automatically dilute stock standards and samples up to 400 times. Agilent has developed the ADS 2 to improve the efficiency and cost-per-sample of elemental analyses by automating calibration, sample dilution, and the reanalysis of out-of-range samples.

Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a versatile multi-elemental analysis technique that is widely used across various sectors due to its high sensitivity and selectivity. Many environmental, food, pharmaceutical, and material testing laboratories that rely on high-throughput methods have benefited from the robustness, reliability, and high performance of Agilent ICP-MS instruments. As laboratories look to further reduce inefficiencies in their workflows and lower demands on staff, there is a shift towards automating manual tasks to improve overall productivity.

To manage the large sample loads that are typical of many environmental testing laboratories, ICP-OES users need instruments that deliver fast sample-to-sample analysis times, while generating consistently high-quality results. Agilent has developed the Advanced Dilution System (ADS 2) for Agilent ICP-OES (and ICP-MS) instruments. The ADS 2 is an intelligent autodilution system, which includes an Advanced Valve System (AVS). The system improves the productivity of ICP-OES workflows by automating many manual tasks throughout the analytical sequence.

Single cell ICP-MS (scICP-MS) is increasingly seen as a powerful and fast tool for the measurement of elements in individual cells, mainly due to the high sensitivity and selectivity of ICP-MS. Analysis is performed in the same way as single nanoparticle (spICP-MS) analysis, which has become a well-established technique for the analysis of nanoparticles and particles.

Watch this video featuring Darren Robey and Dr. Wesam Alwan from Agilent Technologies to gain insights into the future trends shaping microplastics research and the challenges of their characterization. Discover the essential components necessary for accurate microplastics analysis and learn how the Agilent 8700 LDIR system addresses these challenges. Offering rapid and precise analysis capabilities, along with easy sample preparation methods that minimize contamination, the Agilent 8700 LDIR system is at the forefront of advancing microplastics research.

Watch this 20-minute educational video by Andreas Kerstan, Agilent Product Specialist in molecular spectroscopy, to gain a comprehensive update on the microplastics landscape and the environmental concerns related to them. Discover the current challenges in microplastics characterization and how Agilent innovative solutions and techniques, including FTIR, LDIR, GC/MS, and ICP-MS, are addressing these issues head-on.

The automated Agilent 8700 LDIR chemical imaging system lets you obtain high-quality images and spectral data faster than ever before. So, you can perform confident large-scale microplastics studies and monitoring activities.

It is estimated that more than 75% of the 8.3 billion metric tons of plastic produced over the last 65 years have turned into waste. Up to 13 million metric tons of this waste ends up in the ocean every year and recent calculations estimate that more than 5.25 trillion plastic particles float in the world’s oceans. Scientists have demonstrated the alarming environmental ubiquity and persistence of particulate plastic in aquatic ecosystems. Models predict that approximately 14% of the plastic debris in the ocean surface layer can be classified as so-called microplastics (often referred to as particles between 1 µm and 5 mm in size). These ingestible and potentially harmful particles have been formed by UV-induced, mechanical, or biological degradation of larger debris items. To verify the estimates and to meet upcoming regulatory measures (e.g., California Senate Bill 1422) and directives (MSFD, 2008/56/EC), accurate, time-efficient, and robust analytical workflows and techniques are required.

Plastic pollution has become a high-priority area of study in recent years due to the increasing prevalence of plastics in the environment. Currently, researchers have a limited understanding of the impact of plastic pollution on human health, how it affects wildlife and their habitats, and its long-term effects on the environment. An important step in overcoming this pressing global environmental issue is the advancement of research relating to the identification of plastic waste and microplastic particles.