Verification of Common Stearates Without Complex Chemometrics with Agilent Vaya SORS
Magnesium, calcium, or zinc stearates are commonly used in pharmaceutical drug manufacturing. While these metal stearates exhibit similar chemical properties, they are not necessarily interchangeable in manufacturing processes. It is critical therefore that they are identified and differentiated at receipt in the warehouse to avoid process disruptions. Accurately differentiating stearate analogs at receipt by Raman spectroscopy has historically been challenging. Given the similarities of the spectra of the compounds, sophisticated chemometric software is often needed to build stearate models that are then used to identify them. This study shows that the Agilent Vaya handheld Raman spectrometer with Spatially Offset Raman Spectroscopy (SORS) can identify metal stearates in their original primary packaging, without the need for complex chemometric software packages. The handheld Vaya Raman enables the selective verification of stearates using a two-criteria decision algorithm combined with the "Analogous Sample" software feature.
Poster Presentation - RISE imaging of various phases of SiC in sintered silicon-carbide ceramics
November 12th 2024In this poster presentation applications manager Ute Schmidt discusses the use of correlative Raman-SEM (RISE Microscopy) imaging for analyzing silicon-carbide (SiC) ceramics. The main focus of the work is investigating the distribution of sub-micron structured polytypes of SiC grains on and below the surface.
FT-IR gas analysis of coal-to-ethylene glycol process
October 31st 2024Coal-to-ethylene glycol is the process by which ethylene glycol is synthesized from coal instead of traditional methods using petroleum as the raw material. This study demonstrates that Fourier Transform Infrared Spectroscopy (FT-IR) can be a reliable alternative to simultaneously measure methyl nitrite and other process gases (such as CO and NO) using a single ABB analyzer.
