Spectroscopy Year in Review: The Most Popular Articles of 2023
The end of the year is as good a time as ever to reflect.
Here at Spectroscopy, this often means sifting through our most read content. This year, our most popular articles include a mix of stories about notable analytical scientists, artificial intelligence, regulations, and more.
Below, you’ll find an assortment of our most popular news articles, columns, Q&As, and features, in no particular order.
What was your favorite article that ran in Spectroscopy this year? Send me an email at chroncich@mjhlifesciences.com and let me know.
Happy reading!
Infrared Spectroscopy of Polymers X: Polyacrylates
By Brian C. Smith
© Sebastian Duda - stock.adobe.com
Acrylate polymers are derivatives of acrylic acid but contain a plethora of different functional groups and are best discussed by themselves. In this column, we study the spectrum of an important polymer, polymethyl methacrylate (PMMA), which is otherwise known as plexiglass, and is found in windows, car parts, and paint. We then study the spectra of PMMA mixtures and copolymers in detail.
Craig Prater to Receive Coblentz Society’s 2023 Williams-Wright Award
By Aaron Acevedo
© andy_di - stock.adobe.com
Craig Prater was named the 2023 recipient of the Williams-Wright Award, which is given out annually by the Coblentz Society. He was recognized at Pittcon 2023, which took place in Philadelphia, Pennsylvania. Read more to learn about his career.
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Infrared Spectroscopy Reveals Sorption Mechanism of Organic Compounds on Mineral Composite Material
By Spectroscopy Staff
© Weerayuth - stock.adobe.com
Scientists have investigated the sorption mechanism of organic compounds on a mineral composite sorbent using infrared spectroscopy providing insights for the development of effective wastewater purification methods.
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Artificial Intelligence in Analytical Spectroscopy, Part I: Basic Concepts and Discussion
By Jerome Workman Jr.
© NicoElNino - stock.adobe.com
Artificial intelligence (AI), and its subfield machine learning (ML), are major buzzwords in today’s technology world. In a two-part series, let’s begin to look under the hood and behind the scenes to see what AI is and its applicability to analytical chemistry and spectroscopy for future discussion and elaboration. What are the benefits and limitations, as well as the praises and detractions, of AI? How does AI relate to chemometrics?
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Monitoring Soil Quality Using MIR and NIR Spectral Models: An Interview with Felipe Bachion de Santana
By William Wetzel
© Mayatnikstudio - stock.adobe.com
Felipe Bachion de Santana of Teagasc in Wexford, Ireland, is exploring new ways to monitor soil quality through using spectroscopic techniques. Read more about his work in this Q&A.
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The 2023 Emerging Leader in Molecular Spectroscopy Award
By Jerome Workman Jr.
Photo Credit: Glen Jackson
This year’s Emerging Leader in Molecular Spectroscopy Award recipient is Dmitry Kurouski, an assistant professor of chemistry at the Texas A&M University in College Station, Texas. From his early research days as a graduate student at State University of New York in Albany, Kurouski’s research has emphasized the development and application of innovative Raman spectroscopy methods for noninvasive, nondestructive analyses of biological materials.
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CSA: Much Ado About Nothing?
By R.D. McDowall
© JHVEPhoto - stock.adobe.com
Computerized system validation (CSV) in good practice (GxP)-regulated laboratories is alleged to take ages and generate piles of paper to keep inspectors and auditors quiet. To the rescue is the draft FDA guidance on computer software assurance (CSA). But...is this really the case?
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High-Sensitivity Mid-IR Absorption Spectroscopy for Proteins in Aqueous Solution
By John Chasse
© Grandbrothers - stock.adobe.com
Although infrared (IR) absorption spectroscopy can quantify complex biomolecules and their structural conformations, analyzing proteins in aqueous solutions with the technique can be a challenge since strong IR absorption of water will overwhelm the detection system’s limited dynamic range. As a result, the yield is only a very short path and a limited concentration sensitivity. Young Jong Lee and his colleagues at the Biosystems and Biomaterials Division of the National Institute of Standards and Technology in Gaithersburg, Maryland, have developed a solvent absorption compensation (SAC) approach which, by distinguishing the analyte signal over the full dynamic range at each wavelength, can improve the sensitivity of the concentration and extend the available path length. Lee spoke to Spectroscopy about this approach.
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40 Years Old and Still Solving Problems: Evolution of the ICP-MS Application Landscape
By Robert Thomas
© tilialucida - stock.adobe.com
The year 2023 marks the 40th anniversary of the commercialization of inductively coupled plasma mass spectrometry (ICP-MS). Today, there are close to 2000 ICP-MS systems installed worldwide every year, representing around $400M in annual sales. These instruments are used for a wide variety of applications, from routine, high throughput multielement analysis to more complex tasks, such as trace element speciation studies with high-performance liquid chromatography and monitoring of nanoparticles. My column this month will look at the evolving ICP-MS marketplace, highlighting current application trends (compared to other analytical spectroscopy techniques), and where the technique might be heading 5–10 years from now.
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Guess Who’s Coming to Inspect R&D?
By R.D. McDowall
© Grandbrothers - stock.adobe.com
A new revision to the U.S. Food and Drug Administration (FDA)’s Compliance Program Guide for Pre-Approval Inspections (PAIs) has added a fourth objective: Commitment to Quality in Pharmaceutical Development.
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Cancer Diagnosis: New Raman Spectroscopy Method Eliminates Fluorescence Interference
January 21st 2025Researchers from Tsinghua University have developed an innovative dual-wavelength Raman spectroscopy method that eliminates fluorescence interference in measuring esophageal tissue samples. This development enables precise identification of molecular changes in these tissues, with potential applications in early esophageal cancer diagnosis.
Raman Spectroscopy to Detect Lung Cancer and Monitor Vaccine Effects
January 20th 2025A new study highlights the use of Raman spectroscopy to detect lung cancer and evaluate the effects of the PCV13 vaccine. Researchers found distinct biochemical changes in lung cancer patients and healthy individuals, revealing the vaccine's significant impact on immune response.
Nanometer-Scale Studies Using Tip Enhanced Raman Spectroscopy
February 8th 2013Volker Deckert, the winner of the 2013 Charles Mann Award, is advancing the use of tip enhanced Raman spectroscopy (TERS) to push the lateral resolution of vibrational spectroscopy well below the Abbe limit, to achieve single-molecule sensitivity. Because the tip can be moved with sub-nanometer precision, structural information with unmatched spatial resolution can be achieved without the need of specific labels.
An Inside Look at the Fundamentals and Principles of Two-Dimensional Correlation Spectroscopy
January 17th 2025Spectroscopy recently sat down with Isao Noda of the University of Delaware and Young Mee Jung of Kangwon National University to talk about the principles of two-dimensional correlation spectroscopy (2D-COS) and its key applications.
