The University of Dundee (Dundee City, Scotland) has updated its X-ray crystallopgraphy facility with an advanced automated protein crystallography system from Rigaku Americas Corporation (The Woodlands, Texas).
The University of Dundee (Dundee City, Scotland) has updated its X-ray crystallopgraphy facility with an advanced automated protein crystallography system from Rigaku Americas Corporation (The Woodlands, Texas). The new equipment will be used for research in single crystal X-ray diffraction. With access to a more intense X-ray source, a more sensitive detector, and robotics to improve efficiency, researchers at Dundee may now expand structural studies research addressing fundamental aspects of biology together with key issues in human health.
The university’s new equipment is funded by a grant from the charitable foundation, the Wellcome Trust (London, England). The grant, awarded to Professors William Hunter, Daan van Aalten, David Lilley, Tom Owen-Hughes, and Pau Wyatt, will support a range of projects—from the most challenging studies on nucleic acid structures, multi-protein complexes, and enzymes that inform on basic aspects of biology—to the characterization of protein ligand complexes that support early stage medicinal chemistry and drug discovery efforts.
Best of the Week: EAS Conference Coverage, IR Spectroscopy, Microplastics
November 22nd 2024Top articles published this week include highlights from the Eastern Analytical Symposium, a news article about the infrared (IR) spectroscopy market, and a couple of news articles recapping spectroscopic analysis of microplastics.
FT-IR Analysis of pH and Xylitol Driven Conformational Changes of Ovalbumin–Amide VI Band Study
November 21st 2024This study uses Fourier transform infrared (FT-IR) spectroscopy to analyze how the globular protein ovalbumin's secondary structures transition under varying pH conditions in the presence of the cosolvent xylitol, highlighting the role of noncovalent interactions in these conformational changes.