The Use of Raman Spectroscopy in the Pharmaceutical Industry – from Discovery to the Warehouse
Raman spectroscopy has been utilized in the pharmaceutical community for years. Raman works best for raw material identification, polymorphic studies and high throughput screening. However, many active ingredients exhibit fluorescence precluding the use of Raman. A new hand-held Raman spectrometer is now available for users to analyze samples utilizing new patented fluorescence mitigation methods. This new spectrometer has a wide spectra range, high spectral quality for optimizing the analysis, resulting in virtual elimination of false positive/false negative test results.
FT-IR Spectral Fingerprints Reveal Secrets of Rubies and Sapphires
May 14th 2025Scientists at the University of Barcelona have developed a fast and reliable way to identify natural, treated, and synthetic rubies and sapphires using Fourier-transform infrared (FT-IR) spectroscopy. Their study reveals unique spectral fingerprints for different gemstone types, offering a powerful tool in the fight against gem fraud.
Exploring Data Transforms in Chemometrics
May 14th 2025Our “Chemometrics in Spectroscopy” column highlights the methodology that is used in order to apply chemometric methods to data. Integrating chemometrics with spectroscopy allows scientists to understand solutions to their problems when they encounter surprising results. Recently, columnists Howard Mark and Jerome Workman, Jr., wrote a series of articles about data transforms in chemometric calibrations. In this listicle, we profile all pieces in this series and invite you to learn more about applying chemometric models to continuous spectral data.
How Spectroscopy and Science are Reshaping Gemology
May 13th 2025A historical and technical overview from the Gemological Institute of America (GIA) explores how advanced scientific instruments—particularly spectroscopic methods—have transformed gem identification. From refractometers to modern spectrophotometers, this deep dive highlights the evolving challenges and solutions in gem testing.
