Eugene Ma

This article introduces a new infrared (IR) technique, microfluidic modulation spectroscopy (MMS), that is designed to address these needs, and presents data from measurements of commercially available proteins. The data demonstrate significant increases in sensitivity, dynamic range, and utility for the determination of protein similarity (fingerprinting), quantitation, protein secondary structure, and protein stability and aggregation through thermal and chemical denaturation methods.

This article introduces a new IR technique, microfluidic modulation spectroscopy (MMS), that is designed to address the needs in biotherapeutics, and presents data from measurements of commercially available proteins.