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Ivana Mrvalj

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Articles

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Microwave Digestion of Pharmaceutical Finished Products and Ingredients for Upcoming USP Method 233

Daniel Iverson;Jason D. Keith;Ivana Mrvalj;Tina Restivo;CEM Corporation
February 1st 2012

Current USP Method 231 "Heavy Metals" was introduced in 1905 for determining heavy metal impurities in pharmaceutical drug products. The procedures of the method have several limitations, which produce results that are nondiscriminatory, difficult to reproduce, and qualitative, or at best, semi-quantitative.

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