Spectroscopy July 2020
A Further Leap of Biomedical Raman Imaging
July 1st 2020In the past decades, we have witnessed the evolution of imaging technologies based on vibrational spectroscopy. In particular, the technical developments in Raman, coherent anti-Stokes Raman spectroscopy (CARS), and stimulated Raman scattering (SRS) microscopy allow researchers to gain new insights in biological, medical, and pharmaceutical studies.
Single-Cell Analysis by ICP-MS—Current Status and Future Trends
July 1st 2020Single-cell analysis is important in biology and medicine, because it takes into account cell heterogeneity and cellular dynamics, which are governed by cellular crosstalk and the vicinity of cells. Thus, it is of utmost importance to obtain not only information about the heterogeneity of a cell population, but also about their spatial arrangement.
Single Particle ICP-MS: From Engineered Nanoparticles to Natural Nanoparticles
July 1st 2020Single-particle inductively coupled plasma–mass spectrometry (spICP-MS) is becoming widely used to measure the number of nanoparticles (or other submicrometer– sized particles) per mL with a particular elemental chemical composition and the average particle size (diameter) or particle size distribution.
LIBS Imaging Is Entering the Clinic as a New Diagnostic Tool
July 1st 2020Great interest has recently aroused in the study of the dysregulation of chemical elements within tissues. Information about the distribution of elements in biological tissues can contribute to a more complete medical diagnosis, and can guide therapeutic procedures for many pathologies.
Combining Spectroscopy with Microscopy for Advancing the Analysis of Forensically Relevant Traces
July 1st 2020Forensic traces are physical remnants of past events that provide critical information for criminal and civil investigations and adjudications. The scientific examination of traces is an incredibly valuable tool for forensic investigations, because the skilled interpretation of traces yields factual answers to a range of pertinent questions.
Multicollector ICP-MS and Isotope Metallomics
July 1st 2020Although not as widespread in terms of units used worldwide as quadrupole-based inductively coupled plasma–mass spectrometry (ICP-MS) equipment, also multicollector ICP-MS (MC-ICP-MS) instrumentation has revolutionized many fields.