Product Resources

Autosampler

Agilent's model 7693A Automatic Liquid Sampler autosampler is designed to minimize operator variability by automating sample preparation steps. According to the company, the instrument provides better than 1% RSD for sample volumes ranging from 50 nL to 250 μL. The company's Automation Engine software reportedly allows users to create sample preparation protocols without knowledge of programming languages. Agilent Technologies, Santa Clara, CA; www.agilent.com

LC–MS system

The Exactive benchtop LC–MS system from Thermo Fisher Scientific is designed for high throughput, high performance screening and compound identification applications. The system is based on the company's Orbitrap mass analyzer. The system's Pathfinder software reportedly enables users to tune and optimize the system, develop methods, and review data. Thermo Fisher Scientific, Waltham, MA; www.thermo.com/exactive

Quadrupole TOF MS system

The Xevo QTof MS system from Waters can be paired with the company's ACQUITY UltraPerformance LC system and will provide exact mass MS-MS data. The benchtop system reportedly requires minimal sample amounts to provide mass spectral data. Waters Corp., Milford, MA; www.waters.com

GC–MS system

The GUARDION-7 portable GC–toroidal ion-trap MS system from Torion Technologies is designed for rapid, high resolution separation of analytes with mass-based detection of a wide variety of compounds. The system reportedly is supported with the company's CHROMION- operating software and CUSTODION solid-phase microextraction syringes for sample introduction. Torion Technologies Inc., American Fork, UT; www.torion.com

MALDI MS system

The AB SCIEX TOF/TOF 5800 MS system from Applied Biosystems/MDS Analytical Technologies is designed to help researchers advance the discovery of biomarkers to improve the understanding of diseases for potential use in a clinical setting. The MALDI-based system reportedly enables researchers to identify 30% more proteins 10 times faster than other MALDI systems. Applied Biosystems/MDS Analytical Technologies, Foster City, CA; www.appliedbiosystems.com

MS system

The maXis tandem MS system from Bruker Daltonics is designed to provide accurate mass data with high resolution and sensitivity. The system reportedly can be used with UHPLC for applications such as small molecule identification, trace analysis studies, metabolomics, and quantitative proteomics. According to the company, the system's MS and MS-MS mass accuracy is typically 600–800 ppb at acquisition rates as high as 20 full spectra/s. Bruker Daltonics, Billerica, MA; www.bdal.com

Chiral HPLC columns

Epitomize chiral stationary phases from Orochem Technologies are designed for high efficiency chiral molecule separations. The stationary phases are available with 1.7-, 3-, 5-, 10-, 50-, and 100-μm particle sizes with 100-, 300-, and 1000-Å pore sizes in columns ranging from analytical to preparative scale. Orochem Technologies, Lombard, IL; www.orochem.com

TOF detector

The UltraFast BiPolar TOF detector from PHOTONIS is designed to provide a temporal resolution of 750 ps. According to the company, field tests show a nearly twofold increase in mass resolution capability. PHOTONIS, Sturbridge, MA; www.psplc.com

DESI ion source

The 2-D Omni Spray ion source from Prosolia is based on a desorption electrospray ionization (DESI) design. According to the company, the source features a robust surface platform, rapid sampling, software control with an intuitive user interface, and a capacity of three Omni Slides or one Omni Slide-96. The source reportedly is compatible with Thermo and Sciex mass spectrometers. Prosolia, Inc., Indianapolis, IN; www.prosolia.com

HPLC-chip MS system

The HPLC-chip MS system from Agilent is designed to enable automation of phosphopeptide analysis workflow for studying cellular phosphorylation events. The system includes a reusable, nanoflow-rate chip that contains an enrichment section with titanium dioxide beads flanked on both sides with C18 reversed-phase material. The chip reportedly can be used with the company's various MS systems and HPLC-chip cube interface. Agilent Technologies, Santa Clara, CA; www.agilent.com

Miniature mass spectrometer

The Miniature mass spectrometer from 1st Detect is an ion trap–based chemical detector designed for field-portable and handheld applications. According the company, the instrument was designed using advances in low power electronics and miniaturization techniques developed for the Space Program. The instrument reportedly is smaller and lighter than currently available comparable instruments. 1st Detect, Austin, TX; www.1stdetect.com

MS primer

An 80-page MS primer from Waters Corp. is designed for practicing analytical chemists with more than an intellectual curiosity about mass spectrometry. Topics include making ions, mass spectrometer types, accuracy and resolution, and the role of liquid chromatography in performing better mass spectrometry. Waters Corp., Milford, MA; www.waters.com/primers