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Creating uniform and repeatable monolayers is incredibly important for both scientific pursuits as well as the manufacturing of products in semiconductor, biotechnology, and. other industries. However, measuring monolayers and functionalized surfaces directly is. difficult, and many rely on a variety of characterization techniques that when used together can provide some degree of confidence. By combining non-contact atomic force microscopy (AFM) and IR spectroscopy, IR PiFM provides sensitive and accurate analysis of sub-monolayer of molecules without the concern of tip-sample cross contamination. Dr. Sung Park, Molecular Vista, joined Spectroscopy to provide insights on how IR PiFM can acquire IR signature of monolayer films due to its unique implementation.

Elena Hagemann, Product Manager for Process Spectroscopy at Metrohm USA, discusses a novel synchronized, automatic calibration data collector. This system eliminates the laborious calibration process of prediction model development without manual sampling. This capability allows moisture measurement systems to be calibrated at the factory down to approximately 7 ppm and to be installed in pipelines and reactors without additional calibration effort.

In this episode, Damon Strom from WITec’s marketing department, recounts how alphaCART, their portable, research-grade Raman system, joined the alpha300 line of production instruments. Listen to the podcast for a rare glimpse into the development process at Raman microscopy’s most innovative shop.

Bruker’s Surface Sensitive AFM-IR technology provides high-resolution surface sensitivity, reducing chemical probing depth to under 30 nanometers.

When it comes to high-purity inorganic raw materials, the key to analytical success is knowing how to define purity. A variety of factors can impact this definition, including the specific application as well as the chemist’s needs.

As the threat of the opioid epidemic evolves and public health is put at risk, technology is an invaluable resource. Fortunately, libraries for handheld Raman spectroscopy can optimize the identification of bulk and near-bulk fentanyl.

ABB Measurement and Analytics’ Quebec factory marks half a century of advanced analytical solutions.

For over a decade, Senior Product Scientist Derek Guenther has developed, tested and utilized Ocean Optics spectrometers for applications from reflectance of spacecraft metals to catching counterfeit Nike Air Jordans. In this episode, Derek shares insights on recent application challenges and the tools and techniques to take them on.

Modern ICP-OES technology allows for fast and easy determination of the elemental impurities in all components of lithium-ion batteries, enabling researchers to maximize energy density, longevity, and safety.

Microplastics are an emerging issue and the quality of microplastics research is hindered due to their unique physical and chemical characteristics.

Advances in UV-Vis-NIR spectrophotometry instrumentation bring notable gains in analytical performance, productivity, and application flexibility.

Dr. Derek Nowak discusses PiFM, an AFM-IR-based technique, to explain how IR spectroscopy and imaging can be extended to the nanoscale. With sub 5 nm lateral resolution and single-molecule-level sensitivity, PiFM opens up a wide variety of research avenues ranging from exploring nano-crystallin structures for drug delivery to process/failure analysis in semiconductor nanofabrication.

Learn how careful selection of a HP-SIS can help your laboratory achieve optimum analytical performance and reduce operating costs with your inductively coupled plasma-optical emission spectroscopy (ICP-OES).

A successful strategy for speeding the product-development cycle without impairing innovation or quality.

With the rising consumption of protein, there has been a focus on non-animal alternatives. Six primary sources that are now available or in development for commercial use in the food chain include: animal-based proteins (ABP), plant-based proteins (PBP), fermentation-based proteins, insect-based proteins, cell culture-based proteins, and hybrid proteins. With a call for testing, Agilent has solutions for every step of the process.

With the rise of alternative sources of protein, manufacturers of protein substitutes must ensure the safety and nutritional content of their products. Therefore, measuring heavy metals and nutrient elements is an important part of any food quality system. Inductively coupled plasma mass spectrometry (ICP-MS) is the ideal technique for this application.

Analyzing particles directly on gold-coated filters with a laser-based IR chemical imaging system can improve microplastics identification.

Inductively coupled plasma mass spectrometry (ICP-MS) has proven to be an excellent tool for measuring heavy metals and other elements of interest in alternative proteins. A recent study analyzed a range of plant-based and insect-based alternative proteins according to FDA EAM Method 4.7 on the Agilent 7850 ICP-MS with highly successful results. Strategies for achieving confidence in the data were also developed. 

Learn more about several innovative techniques that can shorten time-to-market, reduce development costs, increase yield, and assure quality and pharmacopoeia compliance throughout the drug development process.