Exploring Spectroscopy with the Analytically Speaking Podcasts

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Analytically Speaking Podcast logo

The Analytically Speaking podcast, produced by Spectroscopy and LCGC, is a valuable resource for professionals and researchers in analytical science.

The Analytically Speaking podcast delves into key advancements in spectroscopic techniques, instrumentation, and data analysis. Topics include near-infrared (NIR), infrared (IR), Raman, and other spectroscopic methods, as well as discussions on chemometrics, calibration strategies, artificial intelligence (AI), machine learning (ML), and emerging trends in spectroscopy-driven research. Whether addressing fundamental principles or cutting-edge applications, the podcast offers deeper insights from leading experts in the field.

Each episode is accompanied by a set of show notes that include references, suggested readings, and relevant website links. These notes provide listeners with valuable resources to explore the topics further through their own research.

Listeners can find these spectroscopy-focused podcast episodes on Apple Podcasts, Spotify, and SoundCloud, as well as on the Spectroscopy and LCGC websites. Here are the spectroscopy related podcasts, with their respective links, listed from the 1st episode until the most recent one, episode 33.

Ep. 1: Transmission Infrared Imaging Microscopy (with Data Analytics)

In Episode #1, I interviewBarry Lavine of the Department of Chemistry at Oklahoma State University. Lavine and his research group have been working on new approaches and algorithms for identification and classification of samples measured using infrared (IR) imaging microscopy in forensic analysis. He discusses aspects of sampling, spectra collection, image generation, and data analysis for infrared imaging and sample identification. Data analytics topics include alternate least squares (ALS) reconstruction of the IR spectra of the individual layers from automotive paint samples using ML techniques, spectral database searching, and special experimental design methods.

Ep. 3: The Future of Chemometrics—Data-Driven Measurements and Instruments for Chemistry

In Episode #3, I speak with Karl Booksh of the Department of Chemistry and Biochemistry at the University of Delaware, Newark, who is an expert in Raman and Raman imaging, LIBS, fluorescence, portable chemical sensors, miniaturization of analytical devices, and data driven science incorporating many chemometrics and data analytics techniques. He discusses a National Science Foundation workshop he is organizing with Prof. Barry Lavine entitled, “Data-Driven Measurements and Instruments for Chemistry.”

Ep. 5: New Software Tools for Analysis of Spectroscopic Data

In Episode #5, I interview Paul Gemperline who is Dean of the Graduate School and faculty member in the Department of Chemistry at East Carolina University in Greenville, North Carolina. We have invited Paul to our Analytically Speaking podcast to discuss his research on the development of new computer algorithms and software tools for analysis of multivariate spectroscopic data.

Ep. 7: At the Scene of the Crime: Using Spectroscopy for Forensic Analysis

In Episode #7, I interview Igor K. Lednev who is a Distinguished Professor of Chemistry at the University at Albany at the State University of New York. We have invited Lednev to our Analytically Speaking podcast to discuss his research on the various applications of Raman spectroscopy for the identification and analysis of biological fluid stains used for forensic analysis.

Ep. 9: Automating Advanced Chemometric Methods for Data Processing

In Episode #9, I interview podcast guest Rasmus Bro, who is a full professor at the University of Copenhagen and one of the foremost active living data analytics and chemometrics experts. We spoke to Prof. Bro about the world of data analysis used for spectroscopy and other analytical methods. Over the years he has worked on many aspects of chemometrics, developing numerous algorithms and methods such as fuzzy logic, deep learning, analysis of variance, and tensor modeling. He has received multiple awards in chemometrics and in the analytical sciences, and is the second-most-cited scientist within the field of chemometrics with nearly 37,000 citations and an h-index of 78 (Google Scholar). Most of the algorithms and data sets he has worked on have been made publicly available on the internet. We have invited Prof. Bro to our Analytically Speaking podcast to discuss his research on the development and automation of several chemometrics methods for use with any spectroscopic technique.

Ep. 11: Advancing NIR Spectroscopy Research and Applications

In Episode #11, I talk to Yukihiro (Yuki) Ozaki, who is a professor emeritus in the School of Science and Technology at Kwansei Gakuin University in Japan. He has been a guest professor or scientist at Kobe University and the Toyota Physical and Chemical Research Institute.

We spoke to Ozaki about his theoretical and advanced applications-oriented studies using near-infrared spectroscopy. Yuki is involved in studies of a wide range of molecular spectroscopy techniques, covering from far-ultraviolet to far-infrared–terahertz spectroscopy and also Raman spectroscopy. He is a rather rare scientist who has carried out research in both electronic and vibrational spectroscopy. Yuki has been a member of the Society for Applied Spectroscopy (SAS) for more than 30 years and a Fellow since 2013. He has received several awards, including the Bomem-Michelson Award (2014), the Chemical Society of Japan Award (2017), the Pittsburgh Spectroscopy Award (2019), and the Charles Mann Award (2020).

Ep. 13: Recent Advances in Fluorescence Spectroscopy: Standards and Applications.

In Episode #13, I interview Paul C. DeRose, who is a senior research chemist at the National Institute of Standards and Technology (NIST) and leads the NIST Biochemical Science Division's project in luminescence standards development for chemical analysis and assay validation.

We spoke to Paul about his current research interests in fluorescence and luminescence spectroscopy, specifically concerning the development of fluorescence standards and methods for validation of chemical and clinical assays. Paul’s research has resulted in publications in various areas of fluorescence spectroscopy and microscopy. He has developed fluorescence standard guidelines and recommendations for ASTM, IUPAC, and the U.S. Pharmacopeia. He is also the chair of ASTM E13.01.01 sub-committee on Molecular Luminescence.

Ep. 15: Building Professional Spectroscopy Skills and Valuable Networks with the Coblentz Society

In Episode #15, I speak with Ellen Miseo and Zac Schultz about the benefits of participating in the Coblentz Society.

Miseo has been involved in vibrational spectroscopy and instrument development her entire career and is trained as a physical chemist. She has worked for instrument companies as well as run laboratory operations. She is past president of both the Coblentz Society and Society for Applied Spectroscopy. She currently heads Miseo Consulting.

Schultz is Professor of Chemistry and Biochemistry at The Ohio State University and is the current President of the Coblentz Society. He is widely published on the subject of vibrational spectroscopy and also has an interest in undergraduate science education, and professional development, advancement, and mentoring.

Ep. 17: What’s New in the Field of Atomic Spectroscopy

In Episode #17, we interview Jake Shelley about the latest developments and research in the field of atomic spectroscopy. Shelley is the Alan Paul Schulz Professor of Chemistry in the Department of Chemistry and Chemical Biology at Rensselaer Polytechnic Institute (RPI) in Troy, New York. Shelley’s research explores new hardware and software tools for mass spectrometry for improved detection and identification of analytes, particularly in complex matrices. He is an emerging leader in the field of atomic spectroscopy as noted by his academic background, and involvement with journals, conferences, and by multiple awards, publications, and patents. More information and links about Prof. Shelley and his research can be found within our podcast postings.

Ep. 19: Atomic Spectroscopy: Searching for Life in all the Right Places

In Episode #19, we speak with Andreas Riedo about the new developments in atomic spectroscopy, particularly those related to new advances in the field of space research.

Riedo is a Scientist at the Physics Institute, Space Research and Planetary Sciences, at the University of Bern in Switzerland. He received his PhD in physics in 2014 and has been actively involved in the field of space research and planetary exploration since 2010. His work has included the design, development, and qualification of space-capable analytical instrumentation. His interest and work in the field of laser-based mass spectrometry began during his PhD studies with Prof. Peter Wurz at the Physics Institute in the division of Space Research and Planetary Sciences at the University of Bern. As a graduate student, Riedo optimized an existing LIMS system intended for in situ space research. The instrument has been enhanced to perform analysis for quantitative element composition, isotope abundances, depth profiling, and two- and three-dimensional chemical imaging and analysis. In recent years, Riedo developed the ORIGIN instrument consisting of the same mass analyzer used in his previous studies, but adapted for organic molecule detection. More information and links about Dr. Riedo and his research can be found within our podcast posting links.

Ep. 21: Using Reference Standards for Spectroscopic Measurements

In Episode #21, I interview Art Springsteen about the history and challenges associated with reflection and color standards used around the world for optical spectroscopy.

Springsteen is founder and former CEO of Avian Technologies LLC in New London, New Hampshire, and technologist responsible for developing many reflection, wavelength, and color standards used around the world for decades.

Ep. 23: Color My World: The Complexities of Color Measurements

In Episode #23, I speak with Art Springsteen and David Wyble about the challenges of creating color standards and making color measurements using optical spectroscopy.

Ep. 25: How to Interpret Infrared Spectra and How to Develop a Specialized Infrared Analyzer

In Episode #25, I interview Brian C. Smith about the challenges of training scientists to interpret infrared spectra and how to leverage that expertise into building a specialized instrument for analysis of Cannabis.

Ep. 27: Exploring the World of Spectroscopy for Portable and Wearable Systems: Technology and Applications

In Episode #27, our podcast guest Richard Crocombe of Crocombe Spectroscopic Consulting talks about the world of ever shrinking spectrometers. In this podcast we explore the technologies and applications for such portable and wearable systems and the future of spectroscopy in our everyday lives.

Ep. 29: Quantitative Spectroscopy and Wave Optics in Infrared Spectroscopy

In Episode #29, I speak with Thomas Mayerhöfer from the Leibniz Institute of Photonic Technology in Jena, Germany, about quantitative spectroscopy and wave optics in infrared spectroscopy, including the theory, simulation, and modeling aspects.

Ep. 31: Clarifying the Meaning of Chemometrics, Artificial Intelligence (AI), Machine Learning (ML), and Neural Networks (NNs)

In Episode #31, I interview Barry M. Wise, Founder and President of Eigenvector Research, Inc. about the meaning of the terms chemometrics, AI, ML, and neural networks (NNs) within the context of analytical chemistry and process analysis.

Ep. 33: Automating Multivariate Calibrations: Chronicling the Steps for Replacing the Human Brain in Most Calibration Situations

In Episode #33, I speak with Brian G. Rohrback, president of Infometrix, Inc. in Bothell, WA, USA—who has been active in chemometrics research and creating software for complex calibrations and multivariate data analysis since 1983. Infometrix was founded by researchers Bruce Kowalski and Gerry Erickson in 1978. We have invited Rohrback to our Analytically Speaking podcast to discuss his research and experience in automating the process of building multivariate calibrations.

About the Podcast Host

Jerome Workman, Jr. serves on the Editorial Advisory Board of Spectroscopy and is the Executive Editor for LCGC and Spectroscopy. He is the co-host of the Analytically Speaking podcast and has published multiple reference text volumes, including the three-volume Academic Press Handbook of Organic Compounds, the five-volume The Concise Handbook of Analytical Spectroscopy, the 2nd edition of Practical Guide and Spectral Atlas for Interpretive Near-Infrared Spectroscopy, the 2nd edition of Chemometrics in Spectroscopy, and the 4th edition of The Handbook of Near-Infrared Analysis. Author contact: JWorkman@MJHlifesciences.com ●

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