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Cover image courtesy of Agilent Technologies, Santa Clara, California.
Ad Index 34
Articles
Microfluidic Chip-Based Technology as a Growing Trend in LC–MS Analysis 8
Christine Miller and Dayin Lin
A Reproducible Online 2D Reversed Phase–Reversed Phase High–Low pH Method for Qualitative and Quantitative Proteomics 14
Martha Stapels and Keith Fadgen
Recent Trends in the Use of LC–MS-MS for the Testing of Food and Environmental Contaminants 16
André Schreiber and Kristin von Czapiewski
Successfully Identifying Proteins and Their Modifications Using Electron Transfer Dissociation Linear Ion Trap Mass Spectrometry 22
Andreas Huhmer
Nonderivatized Drug-Screen Analysis in Urine with Automated Solid Phase Microextraction and Comprehensive Two-Dimensional GC–TOF-MS 26
John Heim and Scott Pugh
Improving Oligonucleotide Sensitivity and Separation for LC–MS Applications 30
Greg Scott, Matthew Champion, and Michael McGinley
Best of the Week: What You Missed from Pittcon and AAFS
March 14th 2025Top articles published this week include a video interview on the role of near-infrared (NIR) spectroscopy in food and bioanalysis, a recap of an important session at Pittcon, and a dynamic video that summarizes the highlights of the American Academy of Forensic Sciences (AAFS) Conference.
Raman Spectroscopy Aflatoxin Detection Enhances Peanut Safety
March 11th 2025A research team from Jiangsu University has developed a Raman spectroscopy-based method to detect aflatoxin B1 (AFB1) in peanuts with improved accuracy and efficiency. By employing a two-step hybrid strategy integrating backward interval partial least squares (BiPLS) and variable combination population analysis (VCPA), the new model significantly enhances the precision of AFB1 detection, providing a more reliable approach for food safety monitoring.
Advancing NIR and Imaging Spectroscopy in Food and Bioanalysis
March 11th 2025Our full-length interview with Huck covers more than just NIR spectroscopy in food and bio analysis. Spectroscopy sat down with Huck to also discuss current trends going on in spectroscopy, delving into what challenges spectroscopists face today and how they can solve these concerns.