Appendix X: Raman
Additional information from the Raman section of the Pittcon Review article.
Manufacturer: BaySpec, Inc.
Product name: RamSpec
High Resolution 1064-nm Bench-top Raman Spectrometer
New this year: the RamSpec series is now available with ultra-high ~5cm-1 resolution over the full 200-3200 cm-1 spectral range at 1064-nm excitation wavelength.
Used for: Lab, Process analysis
Accessories: Multi-channel configuration, Direct sampling with vial holder, Variety of fiber optic probe options, Calibration samples, Optional NEMA, IP65 enclosure
Measurement Mode: Raman, can be configured with direct coupling with vial holder or multi-channel and interchangeable fiber optic interface with ability to extend out ~400 meters for in-line process monitoring. The RamSpec comes with a Deep-Cooled Camera cooled to -55°C for low light detection (replacing difficult to use liquid nitrogen cooled cameras).
Special features: The longer wavelength 1064 nm excitation laser offers reduced fluorescence interferences for difficult samples not possible to practically measure using 785nm or 830nm.
Software: Spec 2020 Windows-based software. Available as separate product. 1CFR11 compliant. cGMP compliant. May be used in other equipment. Compatible with other manufacturers' equipment.
Suggested applications: highly fluorescent crystallizations in their early stages of production, such as seen with petrochemicals, biofuels, plastics recycling, pharmaceuticals, food and beverages, among others.
Primary benefits: The RamSpec is an ideal replacement for FT-Raman 1064nm instruments, with ruggedized no moving parts reliability and minimal need for service and support.
Features worthy of mention: Ultra high resolution 1064nm of ~5cm-1 out to 3200cm-1 Available in 532nm, 785nm or other excitation wavelengths, Dispersive, no moving parts, High throughput VPG grating, Fast f/1.8 optics, Optimally cooled -55°C solid-state detector (no need for liquid nitrogen cooling), Customizable with multi-channel inputs and variety of fiber optic probes, Optional NEMA, IP65 enclosure
Manufacturer: B&W Tek, Inc.
Product name: i-Raman EX
Raman Spectrometer
New this year: A portable Raman spectrometer with a 1064nm laser.
Used for: Lab, Handheld/portable operation
Dimensions: 6.7 x 13.4 x 11 inches (17 x 34 x 28 cm)
Measurement Mode: Raman Scattering
Specialty accessory description: fiber optic probe, probe holder with XYZ positioning stage, cuvette adaptor, proprietary software.
Special Features: Comprehensive package of sampling accessories, high sensitivity InGaAs array detector, TE cooling, spectral resolution to 9.5cm-1, spectral coverage from 175-2500cm-1, small footprint, lightweight design, low power consumption.
Software: Provided with: BWIQ multivariant analysis software, BWSpec Spectral Acquisition Software, BWID Spectral Matching Software (Optional)
Available as separate product, 21CFR11 compliant, cGMP compliant, may be used in other equipment, compatible with other manufacturers' equipment.
Suggested applications: forensic analysis including narcotics, bioscience & biomedical diagnostics, chemical warfare agent detection, pharmaceutical material analysis, polymer & chemical analysis, environmental science, explosives detection, petroleum analysis, food & agriculture
Primary benefits: 1064-nm excitation reduces fluorescence
Unique features: Patented CleanLaze Technology for Laser Stabilization, Integration Time 0.2mn to >20 minutes, Adjustable Laser Power, Up to 480mW, Deep Cooled InGaAs Array Detector, Spectral Coverage of 175-2500cm-1, Resolution as Fine as 9.5cm-1
Manufacturer: B&W Tek, Inc.
Product name: i-Raman Plus
Raman Spectrometer
New this year: portable Raman spectrometer with smart spectrometer technology
Used for: Lab, handheld operation
Dimensions: 6.7 x 13.4 x 9.2 inches (17 x 34 x 23.4 cm)
Measurement Mode: Raman Scattering
Specialty accessory description: Same as iRaman-EX, above
Special Features: Same as iRaman-EX, above, in addition to high efficiency back-thinned CCD detector, deep cooling and high dynamic range, up to 30 minutes integration time, wide spectral coverage and high resolution measuring out to 4000 cm-1.
Software: BWIQ multivariant analysis software, BWSpec Spectral Acquisition Software, BWID Spectral Matching Software (Optional)
Available as separate product, 21CFR11 compliant, cGMP compliant, may be used in other equipment, compatible with other manufacturers' equipment
Suggested applications: Geology, mineralogy, gemology, bioscience and medical diagnostics, semiconductor & solar inspection, pharmaceutical material analysis, polymer and chemical analysis, environmental science, raman microscopy, forensic analysis
Primary benefits: Spectral Resolution as fine as 3cm-1
Unique features: Patented CleanLaze Technology, 175 cm-1 of the Rayleigh Line (65cm-1 Option Available), Fiber Optic Coupling, Up to 4000 cm-1 Raman Shift Coverage
Manufacturer: B&W Tek, Inc.
Product name: NanoRam
Raman Spectrometer
New this year: compact Raman handheld spectrometer
Used for: Lab, handheld/portable operation
Dimensions: 8.8 x 3.9 x 2 inches (22 x 10 x 5 cm), weight <2.2 lbs
Measurement Mode: Raman Scattering
Specialty accessory description: pointandshoot attachment, vial holder attachment, right angle attachment, additional application specific adapters.
Special Features: a temperaturecontrolled detector, laser stabilization technology, high speed micro-processor
Software: proprietary Nanoram OS, Nanoram ID
Available as separate product, 21CFR11 compliant, cGMP compliant, Wi-Fi synchronization, transfer libraries from one unit to another.
Suggested applications: Material Identification and Verification, Anti-Counterfeiting, At-line Sampling
Primary benefits: Laboratory quality spectra in the palm of your hand
Unique features: Advanced Statistical Algorithms for Identification & Verification, Wi-Fi Communication for Data Sync & Management, Intuitive Software for Technical & Non-technical Users, Sampling Accessories for Almost Any Environment, Easy Library & Data Transfer Capabilities
Manufacturer: Enhanced Spectrometry, Inc.
Product name: EnSpectr RaPort
Handheld Raman & Luminescence Spectrometer and Analyzer
New this year: The RaPort is the first handheld instrument acquiring and analyzing both Raman & Luminescence with high speed and sensitivity.
Used for: Handheld/portable operation
Dimensions: 21x9x28 cm
Measurement Mode: Raman scattering
Special Features: Raman and luminescent measurements over the spectral range from 140 to 4700 cm-1 with resolution of 6-8 cm1. The battery supports over 6 hours of continuous operation. Data transferred via Blue-tooth.
Software: proprietary EnSpectr Professional Software for qualitative and quantitative analysis, instrument control, LabView interface, variety of math computations, user-augmentable database
Available as separate product, 21CFR11 compliant, cGMP compliant, compatible with other manufacturers' equipment
Suggested applications: Raw materials identification, Security control, Forensics in liquids, powders, gels, solid sample types.
Primary benefits: 3 sec per measurement and recognition, resolution of 6-8 cm-1
Unique features: over 6 hours of continuous off-line operation, data transmission via Bluetooth
Manufacturer: Enhanced Spectrometry, Inc.
Product name: EnSpectr M532 Microscope
Raman Microscope
New this year: High spatial resolution (better than 2 µm), spectral resolution 5-6cm-1 and widened spectral range (140-4000 cm-1 )
Used for: Lab analysis
Dimensions: 463 x 235 x 671 mm, about 9,5 kg
Measurement Mode: transmission and reflection
Special Features: 2D scanner (which enables mapping), portability, 3 Mp camera.
Software: proprietary EnSpectr Professional Software for qualitative and quantitative analysis, instrument control, LabView interface, variety of math computations, user-augmentable database
Available as separate product, 21CFR11 compliant, cGMP compliant
Suggested applications: Gemology, Pharmaceutics, Semiconductor and Chemical Industries, Medical diagnostics
Primary benefits: portable and highly sensitive Microscope with a user-friendly software at affordable price.
Unique features: mapping (optional), Adjustment-free laser exchange technology, portability, cost-effectiveness
Manufacturer: Enhanced Spectrometry, Inc.
Product name: EnSpectr MicroKit
Raman Spectrometer and Accessories
New this year: Micro Kit is a complete solution for those who already have a microscope and want to turn it into a Raman-luminescent tool. For the assembled instrument we use a special edition of R532 with high resolution (5-6 cm-1 ) and spectral range 140-4000 cm1), and a 3 Mp camera
Used for: Lab analysis
Measurement Mode: transmission and reflection
Specialty accessory description: kit includes reflection microscopy tool, CCD camera and spectrometer to microscope adjustment platform.
Special Features: analysis of ultra-low concentrations based on SERS proprietary technology, mapping (optional), 3Mp camera supplied, additional light source for measurements in reflection mode.
Software: proprietary EnSpectr Professional Software for qualitative and quantitative analysis, instrument control, LabView interface, variety of math computations, user-augmentable database, spectral line positioning.
21CFR11 compliant, cGMP compliant, may be used in other equipment, compatible with other manufacturers' equipment
Suggested applications: Gemology, Pharmaceutics, Semiconductor and Chemical Industries, Medical diagnostics
Primary benefits: instead of buying a new Microscope a user can upgrade his existing one with the lowest possible expenses.
Unique features: adjustment-free laser exchange technology, cost-effectiveness Spatial resolution better than 2 µm, high spectral resolution (5-6 cm-1), spectral range 140-4000 cm-1
Manufacturer: Enhanced Spectrometry, Inc.
Product name: EnSpectr R532 Raman & Luminescent Analyzer
Raman & Luminescence Spectrometer and Analyzer, 532 nm
New this year: EnSpectr R532 Raman & Luminescent Analyzer
Used for: Lab, Process analysis
Dimensions: 222 mm x 145 mm x 55 mm
Specialty accessory description: EnSpectr R532 is supplied with various types of attachments for identifications of liquids, powders, solids, tablets, SERS substrates, cover plates and materials of any other forms. Additionally it can be mounted on a microscopic sample stage.
Special Features: portability, wide spectral range (140-6030 cm-1), high spectral resolution (5-8cm-1), 20 µm entrance slit, 30 mW (variable), 532 nm single mode laser.
Software: same as Microkit (above)
Available as separate product, 21CFR11 compliant, cGMP compliant, may be used in other equipment, compatible with other manufacturers' equipment.
Suggested applications: Gemology, chemical, bioscience, art & restoration, forensics, education, semiconductors, pharmacy, medical diagnostic
Primary benefits: small dimensions, high quality of measurement, wide spectral range (140-6030 cm-1), high spectral resolution (5-8 cm-1), adjustment-free laser exchange technology, ability to work with vials, cover plates, SERS substrates, materials of irregular forms, tablets; identification through a transparent and colored glass or translucent plastic packaging; analysis of ultra-low concentrations, operation doesn't require any special technical training to operate it.
Unique features: adjustment-free laser exchange technology, variable laser power, portability and small weight (1,5 kg), automatic spectral line positioning, identification of substance within 1 s.
Manufacturer: Enwave Optronics, Inc.
Product name: ASSUR Handheld Raman System
Handheld Raman Spectrometer
New this year: New design for higher sensitivity, lighter weight, upgraded software
Used for: Handheld/portable operation
Dimensions: Approx.: 9.21" X 4" X 8.77" high
Measurement Mode: Raman
Special Features: Portable with PASS/FAIL designation, battery powered, on-the-spot data analysis
Software: ASSUR-ID software
21CFR11 compliant, cGMP compliant
Suggested applications: Incoming raw materials verification; At-line intermediate and final products inspection; Counterfeit drug identification
Primary benefits: Reduces "time to answer", eliminates analysis of acceptable materials, the experts can concentrate on real issues or problems.
Unique features: higher sensitivity, better spectral resolution compared to other handheld Raman systems. Analysis of difficult materials.
Manufacturer: Enwave Optronics, Inc.
Product name: µSense-C Confocal Raman microscope
Confocal Raman microscope
New this year: Affordable High sensitivity confocal Raman microscope
Used for: Lab analysis
Measurement Mode: Raman scattering
Software: RamanReader-CM
Suggested applications: Chemical, biomedical, nanotechnology
Primary benefits: confocal Raman microscope for demanding Raman analysis
Manufacturer: Enwave Optronics, Inc.
Product name: GasRaman-NOCH2
Field Portable Multiple Gas Analyzer, Raman Spectrometer
New this year: New design for higher sensitivity, upgraded software for quantitative gas analysis
Used for: Lab, Process, Portable applications
Dimensions: 17" x 13" x 8"
Measurement Mode: Raman scattering
Special Features: fully integrated, battery-powered, and portable multi-gas analyzer for high PPM to percentage range of gases
Software: RamanReader-G. Available as separate product, cGMP compliant.
Suggested applications: Multiple Gas analysis for mixtures in the lab and in the field
Primary benefits: A field-portable Raman instrument for multi-gas analysis
Unique features: A gas phase Raman analyzer with field portability capabilities
Manufacturer: HORIBA SCIENTIFIC
Product name: XploRA-One
Confocal Raman microscope
New this year: One Shot Functionality for fast, simple operation from acquisition to reporting,Cost effective Confocal Raman microscopy, sensitivity and simplicity
Used for: Lab, Process analysis
Transportable: 567 mm x 480 mm x 355 mm (H x W x D)
Measurement Mode: Raman scattering
Software: LabSpec 6
Suggested applications: Routine and QC measurements of Forensics, materials science, nano-materials, coatings, Graphene, carbon nanotubes, semiconductors, polymers, pharmaceuticals, museum/ Heritage, gemology/mineralogy, bio-chemical analysis, chemical analysis
Primary benefits: The XploRA ONE offers high quality confocal Raman analysis, one-shot operation and simpler user interface, extremely fast and sensitive Raman analysis.
Unique features: One-shot operation and programmable measurement templates for the Raman analysis and identification of samples, fast (ten times faster) confocal Raman imaging
Manufacturer: HORIBA SCIENTIFIC
Product name: LabRAM HR Evolution
High Resolution Raman Spectrometer
New this year: Offers a fully automated, extended wavelength range capability, achromatic optical design with a long focal length, high spectral resolution and wavelength range capability from 200nm to 2100nm
Used for: Lab analysis
Measurement Mode: Raman microscopy. Transmission Raman available.
Specialty accessories: Ultra Low frequency module, Raman transmission accessory
Software: LabSpec 6, may also be used in other equipment.
Suggested applications: Chemical and structural identification
Primary benefits: Both micro and macro measurements. Confocal Raman imaging in 2D and 3D, expanded range of options
Unique features: Dual Path Optics, Fully achromatic over the range 200nm-2100 nm, high spectral resolution from 800mm focal length spectrometer, access to ultra-low frequencies (down to 10cm-1), SWIFT and DuoScan fast Raman imaging technologies, Extended software features (chemometrics, imaging and fluorescence removal options).
Manufacturer: Ocean Optics
Product name: Apex 785 Raman Spectrometer
Raman spectrometer
New this year: high throughput virtual slit design.
Used for: Lab, process analysis
Measurement Mode: Raman scattering
Special Features: Available as standalone spectrometer or as complete Raman system with laser, probe, sampling device and software
Software: Available as separate product
Suggested applications: 785 nm Raman analysis, chemical identification and fingerprinting for life sciences, clinical diagnostics, materials science, counterfeit detection.
Primary benefits: High sensitivity, detector cooling, shorter measurement times, acquires more accurate spectral "signatures" and Raman fingerprint data, better library matching, Lower powered excitation sources
Unique features: High throughput virtual slit design minimizes, Volume phase holographic grating, maximium diffraction efficiency, minimizes light loss
Manufacturer: Ocean Optics
Product name: Ventana 785
Raman spectrometer
New this year: New entry in Elite Series of spectrometers, light sources and accessories, Novel optical designs and components
Used for: Lab, process analysis
Measurement Mode: Raman scattering
Software available as separate product
Suggested applications: chemical identification, materials characterization and life sciences analyses
Primary benefits: Optical design minimizes light loss and enhances image quality, high sensitivity system, well-focused optics, Low noise electronics keeps the noise from overwhelming low light level signals
Unique features: Volume phase holographic grating, high NA fiber power converter, detection of low light levels
Manufacturer: Real-Time Analyzers, Inc.
Product name: Portable Fuel Analyzer
Dispersive Raman Spectrometer
New this year: Portable fuel analyzer which classifies fuel types and predicts properties for diesel and jet fuels.
Used for: Lab, Process, Handheld/portable
Dimensions: 22.0 x 13.8 x 9.0"
Measurement Mode: Backscatter
Special Features: portable, battery powered, MIL-SPEC 810F, Properties measured: cetane index, cloud point, density, distillation, flash point, viscosity, sulfur, aromatics, olefins & saturates, pour point, acid number, lubricity, net heat, freeze point.
Software: Fuel Analysis software to predict 18 properties of diesel and jet fuels
Suggested applications: fuel analysis
Primary benefits: uses 1064 nm laser excitation to avoid Fluorsecence.
Unique features: Extremely rugged, battery operated, field portable, MIL-SPEC 810F, MIL-SPEC 1472
Manufacturer: Real-Time Analyzers, Inc.
Product name: RamanID
Dispersive Raman Spectrometer
New this year: Portable Raman analyzer which can be used to identify raw materials and determine unknown liquids and solids.
Used for: Lab, Process, Handheld/portable operation
Dimensions: 22.0 x 13.8 x 9.0"
Measurement Mode: Backscatter
Software: Library Search Software
Suggested applications: Raw Material Identification
Primary benefits: uses 1064 nm laser excitation to avoid Fluorsecence.
Unique features: Extremely rugged, battery operated, field portable, MIL-SPEC 810F, MIL-SPEC 1472
Manufacturer: Snowy Range Instruments
Product name: Sierra Series Raman systems
Raman Spectrometer
New this year: Sierra Series Raman system. This system is available with 532, 638, 785, or 808 nm excitation. Sampling system permits sample interrogation from side or bottom of a vial, or a point & shoot option includes Orbital Raster Scan (ORS™) technology.
Used for: Lab analysis
Portable, dimensions: 9" x 5.5" x 2.5"; 4 lbs.
Special Features: Orbital Raster Scan (ORS) technology analyses mixtures and shaped samples. Also features Dynamic Raman Scattering (DRS) capability.
Software: Peak Acquisition software. Available as separate product. May be used in other equipment. Compatible with other manufacturers' equipment
Suggested applications: ideal for research and development labs, education labs, SERS development and general Raman scattering analysis.
Primary benefits: high sensitivity spectrograph and the ORS feature provides low level analysis, the averaging of SERS hotspots, and the reduction of the instantaneous laser power density. Capable of performing DRS measurements to analyze low concentration tags or analytes in solvents.
Unique features: unique sampling mechanism, permits user to sample from either the side or bottom of a vial, point & shoot aperture, analyze surfaces.
Manufacturer: Tornado Spectral Systems
Product name: HyperFlux U1 Spectrometer
Raman Spectrometer
New this year: Factory configurable from UV/VIS to NIR, Cooled versions available
Used for: Lab, process, handheld applications
Dimensions: 12.2" (width) X 11.8" (depth) X 4.1" (height)
Measurement Mode: Reflection
Software: Available as separate product, 21CFR11 compliant, May be used in other equipment, Compatible with other manufacturers' equipment
Suggested applications: PAT, SERS, microscopy, TERS, LIBS, R&D
Primary benefits: The HyperFlux U1 offers unmatched performance and customization due to HTVS (high throughput virtual slit), detect weak signals: fluorescence-free anti-Stokes, low-power illumination, 4 cm-1 with no slit using entire input aperture of 200 µm fiber, cooled & uncooled detector options
Unique features: Uses patented HTVS Technology, Fluorescence-free anti-Stokes,
No fixed configuration; we build to your resolution requirements across UV/VIS/NIR
New Fluorescent Raman Technique Enhances Detection of Microplastics in Seawater
November 19th 2024A novel method using fluorescence labeling and differential Raman spectroscopy claims to offer a more efficient, accurate approach to detect microplastics in seawater. Developed by researchers at the Ocean University of China, this method improves both the speed and precision of microplastic identification, addressing a key environmental issue affecting marine ecosystems.
