Application Notes: General
Photoluminescence and Electroluminescence of Organic Optoelectronics
September 13th 2016Photoluminescence and electroluminescence spectroscopy is a useful technique in the investigation of organic optoelectronic devices. The instrumentation for steady-state and time-resolved photoluminescence, as well as electroluminescence, is specified in this application note on organic solar cells.
Using Raman spectroscopy to analyse Li-ion battery anodes
September 8th 2016It is vital to be able to rapidly and easily analyse the composition and structure of anodes. The inVia is ideal for locating, discriminating, and quantifying the different forms of carbon present in anodes, even those with subtle variations in structure.
Inorganic Products: Mining Ores, Catalysts, Superalloys, and Ceramics
August 17th 2016The Milestone UltraWAVE can digest up to 22 different sample types simultaneously. The high temperature and pressure capability enables a complete digestion of nearly all inorganic sample types that need to be analyzed for trace metals.
Discrimination of Lipids in Heart Tissue using DESI HRMS MSI
July 20th 2016Mass Spectrometric Imaging (MSI) using DESI provides molecular imaging without the interference of the matrix required for MALDI and offers the advantage of preserving sample for further analysis. DESI coupled to High Resolution Accurate Mass (HRAM), is shown here to elucidate spatial distribution of lipids, protein, and metabolites in tissue sections and can provide confident and discriminate biomarker determinations.
Non-invasive Combustion Diagnostics
July 7th 2016PLIF, PIV and next generation imaging detectors - Combustion processes, if uncontrolled, are inherently inefficient and increasing the efficiency of combustion in engines, gas burners and furnaces is a significant challenge for the future due to limited fossil fuel resources and their effects on the environment.
Efficient Mitigation of Fluorescence in Raman Spectroscopy Using SSE™
July 6th 2016Handheld Raman spectrometers are now designed and built for practical everyday use in a vast array of applications. The new BRAVO by Bruker takes handheld Raman Spectroscopy to a new level, overcoming the limitations of previously available systems such as limited wavelength accuracy, non-safe laser usage and fluorescence interference. Now with BRAVO wavelength accuracy is significantly better than competitive devices resulting in the highest data consistency and the BRAVO incorporates new technology called Sequentially Shifted Excitation (SSE™) to mitigate fluorescence.
Implementation of MicroNIR PAT for Blend Monitoring
June 13th 2016A wireless NIR spectrometer is deployed on solid dose blending formulation for end-point monitoring. The MicroNIR PAT is democratizing the use NIR spectroscopy in pharmaceutical manufacturing facilitating Quality by Design (QbD) adoption.
GOOD LABORATORY PRACTICE Agilent Cary 8454 UV-Visible Spectroscopy System
June 13th 2016This note looks at specific components that require validation; the instrument, software, and validated test methods, and describes the features of the Agilent Cary 8454 UV-Visible system that is designed to meet the requirements of both initial and recurrent validation.
QA/QC PHARMACEUTICAL SOLUTIONS - Cary 8454 UV-Visible Spectroscopy System
June 13th 2016This note describes how the design of the Cary 8454 UV-Vis exceeds performance requirements stipulated by global pharmacopeia guidelines including USP and EP/BP. Configured for compliance, with 21 CFR Part 11, the instrument performs multi wavelength analysis, time-based kinetics assays, and routine QA/QC measurements.
Agilent Cary 630 FTIR Pharmacopoeia Compliance
June 13th 2016This application note demonstrates how Agilent’s Cary 630 FTIR easily meets the specifications of the US, European, Japanese, Chinese, Indian and International Pharmacopoeia. Its combination of compact size, design, intuitive and regulation-compliant software makes the Cary 630 FTIR an ideal instrument for pharmaceutical quality control.
THE DIODE ARRAY ADVANTAGE for Pharmaceutical QA/QC
June 13th 2016The Agilent Cary 8454 UV-Visible system is ideal for regulatory Pharma QA/QC applications, and can acquire a complete spectrum in less than 1 second. This technical note outlines both applications-based and technical considerations for choosing a diode array UV-Vis
Agilent Cary 630 FTIR Spectrometer Quickly Identifies and Qualifies Pharmaceuticals
June 13th 2016This application note describes a very sensitive classification method, partial least squares–discriminant analysis (PLS-DA), incorporated in Agilent innovative MicroLab software, to classify and qualify materials of interest with greater sensitivity and specificity than possible with simple library search methods.
Infrared Microspectroscopic Imaging of Biological Samples
May 12th 2016FT-IR microscopy constitutes a very fast and efficient alternative to the well-established staining methods. It allows to analyze biological samples with minimal sample preparation and without the need for any agents for contrast enhancement.
How to Achieve Excellent Results for Trace Elements in Petrochemical Samples
April 26th 2016Analysis of trace elements in petrochemical samples is routinely carried out for quality control and process monitoring using protocols set by organizations such as ASTM. However, analysis of these samples is often challenging due to the high matrix and potential for interferences. This executive summary will provide essential information on how to develop robust methods over coming these challenges and ensure excellent results when analyzing trace elements in petrochemicals samples by ICP-OES.