September 4th 2024
Spectroscopic analytical techniques are crucial for the analysis of agricultural products. This review emphasizes the latest advancements in several key spectroscopic methods, including atomic, vibrational, molecular, electronic, and X-ray techniques. The applications of these analytical methods in detecting important quality parameters, adulteration, insects and rodent infestation, ripening, and other essential applications are discussed.
September 4th 2024
Combining Confocal Raman with Atomic force Microscopy for High-Resolution Material Analysis
June 2nd 2005Confocal Raman microscopy can be useful when applied to all samples that are heterogeneous on the micrometer to millimeter scale and that generally can be investigated by Raman spectroscopy. This article presents examples of confocal Raman microscopy from various fields of application including pharmaceutical analysis and stress measurements in semiconductors.
A New Approach to Simultaneous Raman and IR Spectral Searches
June 2nd 2005A new system for multitechnique spectral searching is described that utilizes analysis of several hit lists resulting from spectral similarity searches performed simultaneously in reference databases for multiple complementary analytical techniques. This paper demonstrates the benefits of this multitechnique approach using the complementary techniques of IR and Raman spectroscopy.
Raman and EDXRF Chemical Imaging for Formulation Process Development and Quality Control
June 2nd 2005Compounds of magnesium and calcium are common components of pharmaceutical formulations. Spectroscopic imaging can provide a complete understanding of a formulation. This paper compares two spectral imaging techniques — energy dispersive X-ray fluorescence (EDXRF) microscopy and Raman microscopy.
Grating Corrected Laser Stabilization: A Case Study in Pharmaceutical Raw Material Identification
June 2nd 2005The authors present a novel technique for obtaining very high stability and reproducibility of a Raman spectrum, using grating corrected laser stabilization. An externally stabilized laser with a grating spectrometer provides exceptional quantum efficiency in the entire dynamic range. These components then are used to build a library of pharmaceutical raw materials and tested on samples of unknown material.
Reliable Substrate Technology for Surface-Enhanced Raman Spectroscopy
June 2nd 2005The acquisition of Raman spectra can be eased greatly through the use of surface-enhanced Raman spectroscopy (SERS). In this article, the authors discuss a new substrate technology that delivers reliable and consistent surface enhancement.
Detecting Bacillus Spores by Raman and Surface-Enhanced Raman (SERS) Spectroscopy
June 2nd 2005Raman spectroscopy has been employed to detect Bacillus cereus spores, an anthrax surrogate, collected from a letter as it passed through a mail sorting system. Raman spectroscopy also has the ability to identify many common substances used as hoaxes. A three-step method also is described for the detection of dipicolinic acid extracted from surface spores by SERS.
Comparing Standard CCD and Electron Multiplication CCD for Low Light Level Spectroscopy
June 2nd 2005This article compares different CCD platforms by outlining CCD and EMCCD noise sources as well as an explanation of the two calculations to arrive at the signal-to-noise ratio for each. The data presented will show that a liquid nitrogen-cooled CCD camera still is the proper choice for low light level applications, such as Raman spectroscopy.
Powerful Partners Provide Complete Analytical Solutions (PDF)
June 2nd 2004This article examines advances that have been made to combine existing analytical techniques with Raman instrumentation. Some of these methods offer enhanced sample visualization, while others provide complementary vibrational spectroscopic information from a single sample point.
Raman Microscopy as a Valuable Tool for Failure Analysis (PDF)
June 2nd 2004The authors discuss several sample types encountered in their laboratory for which Raman spectroscopy is the only reliable method of analysis. The technique is shown to be a routine and cost-effective tool for the industrial laboratory.
Raman Spectroscopy for Homeland Defense Applications (PDF)
June 2nd 2004Raman spectroscopy is used routinely by the agencies tasked with homeland defense, and current research using surface enhanced Raman spectroscopy shows promise for the detection of chemical warfare agents and other toxic chemicals. This article overviews some of the latest developments in the field.