CEM Corporation

This application note demonstrates the CEM MARS 6 for microwave digestion of mixed cannabis and hemp containing products in a single run and elemental analysis of these products.

In 1970, marijuana was designated a Schedule 1 drug, under the Controlled Substances Act, making it nearly impossible for laboratories to perform cannabis research. However, medicinal use of cannabis is now legal in Canada and 33 U.S. states.

Better analysis starts with better sample prep, particularly with challenging samples like cannabis and hemp. Learn how to optimize techniques and tools to achieve consistent and complete sample prep for potency, pesticides, and metals analysis. Live: Wednesday, Jul. 24, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST On demand available after airing until Jul 24, 2020 Register free

CEM's Discover SP-D Gold microwave digestion system with high temperature and pressure chamber enables safe, fast, and automated preparation of previously difficult sample types

Pharmaceutical samples spiked with several heavy metals were prepared for ICP-MS analysis using microwave digestion following the protocols in proposed USP chapters <232> and <233>. The results of the spike recovery study are discussed.

Current USP Method 231 "Heavy Metals" was introduced in 1905 for determining heavy metal impurities in pharmaceutical drug products. The procedures of the method have several limitations, which produce results that are nondiscriminatory, difficult to reproduce, and qualitative, or at best, semi-quantitative.