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Exploration of the chemistry of materials at micrometer and nanometer scales leads to a better macroscopic perspective, as illustrated here with examples from our ongoing research in materials, environmental, and biomedical applications

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In this study, micro-Raman microscopy was used to examine graphite mechanical behavior through the evolution of dislocation defect density and the resultant deformation (strain) in graphite components. The increasing strength of the Raman optical phonon modes linked with a generous number of dislocations indicates the potential capability of Raman spectroscopy to help develop a mechanistic understanding of the complex mechanical behavior of graphite for use in many industries and applications.

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Exploration of the chemistry of materials at micrometer and nanometer scales leads to a better macroscopic perspective, as illustrated here with examples from our ongoing research in materials, environmental, and biomedical applications

Latest:

In this study, micro-Raman microscopy was used to examine graphite mechanical behavior through the evolution of dislocation defect density and the resultant deformation (strain) in graphite components. The increasing strength of the Raman optical phonon modes linked with a generous number of dislocations indicates the potential capability of Raman spectroscopy to help develop a mechanistic understanding of the complex mechanical behavior of graphite for use in many industries and applications.

Latest:

Exploration of the chemistry of materials at micrometer and nanometer scales leads to a better macroscopic perspective, as illustrated here with examples from our ongoing research in materials, environmental, and biomedical applications

Latest:

Exploration of the chemistry of materials at micrometer and nanometer scales leads to a better macroscopic perspective, as illustrated here with examples from our ongoing research in materials, environmental, and biomedical applications

Latest:

Exploration of the chemistry of materials at micrometer and nanometer scales leads to a better macroscopic perspective, as illustrated here with examples from our ongoing research in materials, environmental, and biomedical applications

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This article illustrates experience with some new developments in IR spectroscopy, with examples of how this traditional field continues to explode into new territory, enabling rapid acquisition of huge data sets on the one hand, while permitting exploration of chemical composition of targets with nanometer-scale spatial resolution on the other.

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Several spectroscopic measurement techniques are proving to be very effective and versatile for environmental applications.

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Five key qualitative factors–speed, sensitivity, resolution, modularity and upgradeability, and combinability–contribute to the quality of confocal Raman imaging microscopes. Using application examples, this article introduces modern Raman imaging and correlative imaging techniques, and presents state-of-the-art practice examples from polymer research, pharmaceutics, low-dimensional materials research, and life sciences.

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Knowledge of atmospheric ammonia concentrations is important, but ammonia is difficult to measure. We report here on the development of a low-cost ammonia measuring differential optical absorption spectroscopy (DOAS) instrument, based on a small sized and low priced spectrograph.

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The C16767MA miniaturized ultraviolet (UV) spectrometer, developed by Hamamatsu, offers a groundbreaking solution for real-time, on-site water quality monitoring, replacing traditional, labor-intensive methods.

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Researchers from Tsinghua University and Beihang University in Beijing have developed a deep-learning-based data processing framework that significantly improves the accuracy of dual-comb absorption spectroscopy (DCAS) in gas quantification analysis. By using a U-net model for etalon removal and a modified U-net combined with traditional methods for baseline extraction, their framework achieves high-fidelity absorbance spectra, even in challenging conditions with complex baselines and etalon effects.

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SERS can be used for the detection and monitoring of drugs as pure compounds and mixtures. A demonstration of a sample preparation method used to detect components with weak substrate adsorption in the spectrum of a mixed solution is shown.

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SERS can be used for the detection and monitoring of drugs as pure compounds and mixtures. A demonstration of a sample preparation method used to detect components with weak substrate adsorption in the spectrum of a mixed solution is shown.

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This SERS method is rapid, accurate, nondestructive, and easy

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SERS can be used for the detection and monitoring of drugs as pure compounds and mixtures. A demonstration of a sample preparation method used to detect components with weak substrate adsorption in the spectrum of a mixed solution is shown.

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This SERS method is rapid, accurate, nondestructive, and easy

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This SERS method is rapid, accurate, nondestructive, and easy

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Among all the analytical techniques available for epitope mapping studies, hydrogen–deuterium exchange mass spectrometry (HDX-MS) is usually the fastest and easiest to carry out. We present here the epitope mapping of three distinct monoclonal antibody (mAb) candidates targeting the same antigen, an interleukin receptor. The goal is to establish the binding mode of these mAbs, and explain possible differences observed for in vitro binding and in vivo function.

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Among all the analytical techniques available for epitope mapping studies, hydrogen–deuterium exchange mass spectrometry (HDX-MS) is usually the fastest and easiest to carry out. We present here the epitope mapping of three distinct monoclonal antibody (mAb) candidates targeting the same antigen, an interleukin receptor. The goal is to establish the binding mode of these mAbs, and explain possible differences observed for in vitro binding and in vivo function.

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Among all the analytical techniques available for epitope mapping studies, hydrogen–deuterium exchange mass spectrometry (HDX-MS) is usually the fastest and easiest to carry out. We present here the epitope mapping of three distinct monoclonal antibody (mAb) candidates targeting the same antigen, an interleukin receptor. The goal is to establish the binding mode of these mAbs, and explain possible differences observed for in vitro binding and in vivo function.

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The past decade has witnessed resurgent interest in coupling GC to atmospheric-pressure chemical ionization (APCI), which is suitable for the high column flows required for using flow modulation. This study assesses the use of GP-APCI with flow modulation for sensitive detection of selected trace organics.