ICP-MS

Efficient and accurate measurement of mercury concentration is a challenge. A direct sample preparation method for reliable ICP-OES mercury measurement would be invaluable to chemical manufacturers, testing laboratories, and other industries. Historically, ICP-OES Hg measurements have been plagued by poor Hg detection limits, severe carryover effects, and sample instability. In this study, we present a method of sample preparation for ICP-OES mercury analysis in various reagent chemical compounds. This sample preparation method is straightforward and direct, allowing mercury analysis in a variety of reagent chemicals without digestion.

This paper describes the analysis of edible oils radial view ICP-OES. Information is provided regarding the most suitable wavelengths, background correction, and integration times. Results of a detection limit study are presented. The accuracy of the analytical method is validated using soybean, olive, and corn oil matrices.

Matrix effects-changes in analyte sensitivity induced by a high concentration of matrix elements-can reduce accuracy in inductively coupled plasma–mass spectrometry (ICP-MS). It has long been accepted, since the 1987 publication of a study by Tan and Horlick (1), that matrix effects are more severe for light analyte ions in the presence of heavy matrix ions. However, new studies by Shi Jiao and John Olesik in the Trace Element Research Laboratory (TERL) at The Ohio State University (Columbus, Ohio), carried out using current ICP-MS instruments, show that matrix effects are not strongly dependent on analyte ion mass. These study results have implications for understanding the fundamental causes of matrix effects in ICP-MS, and for the choice of internal standards. Jiao and Olesik spoke to Spectroscopy about this work.

Inductively coupled plasma–mass spectrometry (ICP-MS) is a powerful analytical technique. But like any other analytical techniques, there are challenges involved. We recently asked ICP-MS experts what unresolved problems exist-especially with samples in complex matrices-and how ICP-MS methods or technologies can be developed to attack them.

In honor of Spectroscopy's celebration of 30 years covering the latest developments in materials analysis, we asked a panel of experts to assess the current state of the art of inductively coupled plasma–mass spectrometry (ICP-MS) and to try to predict how the technology will develop in the future.

Low-level analysis of food matrices has placed a demand on manufacturers, testing laboratories, and instrumentation vendors worldwide. Stricter regulations, better analytical instrumentation, and greatly improved sample preparation (preanalytical) techniques have focused efforts to simplify and standardize these analyses. Often overlooked, the preanalytical step determines the quality of the resulting data and requires careful attention to a number of details, including sample size, digestion parameters, and the level of detection needed.

Multiple-collector inductively coupled plasma–mass spectrometry (MC-ICP-MS) has some specific advantages over traditional ICP-MS instruments.

A novel approach to handling samples with very high and variable levels of sample matrix is to use aerosol dilution, whereby the amount of sample aerosol that reaches the plasma is reduced by dilution with an additional argon gas stream.

This article compares several performance criteria such as full width at half maximum, background equivalent concentrations, limits of detection, purge requirements, and results for some substances for the "traditional" As lines at 188.979, 193.696, and 197.197 nm for the "new" line at 228.812 nm.

Rare earth elements (REEs) have become indispensable in many electronic, optical, magnetic, and catalytic applications because of their specific properties such as magnetism and phosphorescence, as well as their ability to both donate and accept electrons.

The California Department of Public Health has proposed to establish the first regulatory limit in the United States for hexavalent chromium (chromium-6) in drinking water. The proposed Maximum Contaminant Level (MCL) sets the limit for hexavalent chromium at 10 parts per billion. California, like those of other states and United States federal government, currently only regulates total chromium levels.

A new sodium peroxide fusion method is described, as well as the conditions for inductively coupled plasma–optical emission spectrometry, and a list of the accuracy and precision measurements for all prepared samples.

A critical review of the main developments in instrument technology, calibration, and sample preparation that have made it possible to determine low sulfur concentrations in fuels followed by a discussion of strategies to minimize spectral interferences related to sulfur determination by ICP-MS, such as collision–reaction cells, high-resolution mass analyzers, and the interference standard method.

A look at ICP–MS, ICP–OES, X-ray fluorescence spectroscopy, and laser-induced breakdown spectroscopy in the areas of research and development, marketing, application, and use of these techniques.

Conventional pneumatic nebulizer-spray chamber combinations for ICP spectrometry have a sample introduction efficiency of only 1-3%. A unique electrothermal vaporization device developed by Vassili Karanassios of the University of Waterloo uses field-portable rhenium filament coils with a very small vaporization chamber and increases the sample introduction efficiency to 100%.

The authors have been characterizing an electrothermal, near-torch vaporization (NTV) micro- and nano-sample introduction system for inductively coupled plasma (ICP) spectrometry.

Triple-quadrupole inductively coupled plasma–mass spectrometry (ICP-MS) can operate in MS-MS mode, which offers the potential to improve the removal of spectral interferences compared to conventional quadrupole ICP-MS with a collision–reaction cell, or high-resolution ICP-MS.

Spectroscopy recently spoke with Frank A. Kero, an analytical applications specialist with Biotage, about his research with ICP-MS.

This article highlights the benefits of using ion-molecule chemistry in a quadrupole-based collision–reaction cell to determine titanium levels in the presence of problematic polyatomic spectral interferences encountered in the analysis of human blood and serum samples from patients who have undergone artificial joint replacement surgery.

Spectroscopy recently spoke with Dominic Hare, a senior research officer at the Florey Institute of Neuroscience and Mental Health in Australia, about his work using laser ablation–inductively coupled plasma–mass spectrometry (LA–ICP-MS) to study metals in the brain.

This article describes the direct measurement of trace levels of organometallic process gases in semiconductor manufacturing environments using a gas-exchange device coupled with quadrupole inductively coupled plasma–mass spectrometry (ICP-MS).

Contract analytical laboratories use a variety of instrumentation for trace-metal analysis and must take advantage of method standardization whenever there is an opportunity.

Click here to view the complete Wavelength newsletter from October 8, 2013.

Spectroscopy recently spoke with Dr. Dominic Hare, a senior research officer at the Florey Institute of Neuroscience and Mental Health in Australia, about his work using laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) to study metals in the brain. His research highlights the role that iron plays in Parkinson's disease in the hopes to better understand the causes of the disease and eventually find an appropriate treatment.

Rick Russo, the winner of the 2013 Lester W. Strock Award, is known for important advances in laser ablation for use in spectrochemical analysis. In a new interview, he talks about those developments, how his career developed, and what it's like, as a research scientist, to lead a start-up company.

Spectroscopy recently spoke with Frank A. Kero, PhD, about his research with inductively coupled plasma?mass spectrometry (ICP-MS).

Methods and results from a study analyzing metal concentrations in urine samples using inductively coupled plasma–mass spectrometry (ICP-MS)

Wastewater from coal-fired power plants is linked to a wide range of environmental and human health concerns. Measuring low levels of toxic trace metals in these wastewaters is complicated, however, by high levels of interfering matrix elements. A new EPA method using ICP-MS addresses this analytical challenge.

This article describes a way to measure 226Ra using inductively coupled plasma–mass spectrometry (ICP-MS) rather than the conventional method of gamma spectroscopy, taking into account an undocumented interference (207Pb19F) that is caused by the requirement to use hydrofluoric acid during sample preparation. The unusually high Pb levels observed in a number of soil samples caused significant interferences at the very low concentrations of 226Ra that were measured. The expected 208Pb18O interference was insignificant under optimized instrument conditions.