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Latest:
Test of an In Vivo Method to Detect Chloroplast Division in Crop Plants, Part III: Statistical Proofs of Observation and General Utility of the Method (PDF)This article is the third installment in a series about a novel spectrofluorometric method that allow for in vivo observation of the division of chlorplast populations in leaves of Arabidopsis thalania.
Latest:
FT-IR Spectroscopy: An Advanced Tool for Studying Biomedical Problems (PDF)The authors describe several applications of FT-IR spectroscopy in the biomedical sciences, including characterization of healthy and neoplastic human skin samples affected by two kinds of cancers, and examination of liver damage and regeneration caused by carbon tetrachloride.
Latest:
Unilateral Nuclear Magnetic Resonance for Quality Control: The NMR-MOUSE (pdf)This article discusses the principles of unilateral nuclear magnetic resonance with applications to elastomers and nondestructive in situ inspection of a wet fresco from ancient Rome.
Latest:
IMS for Cleaning Verification (PDF)The need to verify cleaning between manufacturing runs presents a special challenge to the analytical chemist. In this article, the principles of ion mobility spectrometry are described, its performance is compared to HPLC for the analysis of cleaning validation samples, and findings are presented from a study to establish the feasibility of using IMS in validating a cleaning verification method.
Latest:
Tech Note: High-Resolution Ultrasonic Spectroscopy for Analysis of Chemical Reactions in Real Time (PDF)This article discusses direct real-time monitoring of chemical reactions, an important tool in industrial processes in industries such as chemical, biotechnology, food, and pharmaceutical.
Latest:
IMS for Cleaning Verification (PDF)The need to verify cleaning between manufacturing runs presents a special challenge to the analytical chemist. In this article, the principles of ion mobility spectrometry are described, its performance is compared to HPLC for the analysis of cleaning validation samples, and findings are presented from a study to establish the feasibility of using IMS in validating a cleaning verification method.
Latest:
Test of an In Vivo Method to Detect Chloroplast Division in Crop Plants, Part III: Statistical Proofs of Observation and General Utility of the Method (PDF)This article is the third installment in a series about a novel spectrofluorometric method that allow for in vivo observation of the division of chlorplast populations in leaves of Arabidopsis thalania.
Latest:
Considerations for Primary Vacuum Pumping in Mass Spectrometry Systems (PDF)Mass spectrometry systems have specific vacuum requirements. New developments in oil-free, or dry, primary vacuum pumps have been introduced recently and are discussed in this article with respect to capacity, throughput, and specific pumping requirements for process gases.
Latest:
Determination of Recombinant Monoclonal Antibodies and Noncovalent Antigen TNFa Trimer Using Q-TOF Mass Spectrometry (PDF)This article discusses how quadrupole time-of-flight mass spectrometry was used to measure the intact molecular weights of large proteins and some noncovalent protein complexes.
Latest:
Temperature-Induced Effect on Surface-Enhanced Raman Scattering of p,m-Hydroxybenzoic Acid on Silver Nanoparticles (PDF)This article examines temperature-induced effects on surface-enhanced Raman scattering of PHBA and MHBA adsorbed on silver colloidal particles.
Latest:
The Changing Face of LC–MS: From Experts to UsersThe authors discuss the changes that have taken place in the last two decades regarding the users and capabilities of LC–MS.
Latest:
Three-Dimensional Printing and the Art of Making Small Working Prototype SpectrometersA 3D printer can shorten the time to make prototype hardware for spectrometers from weeks to days—or less.
Latest:
How Using Raman Spectroscopy and SIMPLISMA Can Accelerate the Study of Polymorphs: A Case Study Using Carbamazepine (PDF)The authors show how a multivariate curve resolution algorithm, called SIMPLe-to-use Interactive Self-modeling Mixture Analysis (SIMPLISMA), can facilitate the quantitative and qualitative analysis of difficult samples, and apply the algorithm to a technically challenging Raman spectra series for carbamazepine polymorphs.
Latest:
Identifying Macromolecules (PDF)The authors review a surface enhanced laser Raman spectroscopy study of lung surfactant protein interaction with bacterial lipopolysaccharide.
Latest:
Powerful Partners Provide Complete Analytical Solutions (PDF)This article examines advances that have been made to combine existing analytical techniques with Raman instrumentation. Some of these methods offer enhanced sample visualization, while others provide complementary vibrational spectroscopic information from a single sample point.
Latest:
Identifying Macromolecules (PDF)The authors review a surface enhanced laser Raman spectroscopy study of lung surfactant protein interaction with bacterial lipopolysaccharide.
Latest:
FT-IR Spectroscopy: An Advanced Tool for Studying Biomedical Problems (PDF)The authors describe several applications of FT-IR spectroscopy in the biomedical sciences, including characterization of healthy and neoplastic human skin samples affected by two kinds of cancers, and examination of liver damage and regeneration caused by carbon tetrachloride.
Latest:
Laser Ablation Solid Sampling for Plasma Spectrochemistry (PDF)Careful consideration of the dynamics associated with laser ablation solid sampling systems ensures greater analytical precision and accuracy for ICP-MS/OES element analysis.
Latest:
Dealing With the Masses: A Tutorial on Accurate Masses, Mass 32 Uncertainties, and Mass DefectsThis tutorial illustrates the most important definitions used in high-resolution mass spectrometry and clarifies the misconceptions surrounding some of the relevant terms used in this field.
Latest:
PittCon 2002 Review (PDF)Spectroscopy's annual overview of new instrumentation presented at the PittCon conference.
Latest:
A Teachable Moment: “H-Classic Papers in Atomic Spectroscopy”A note from the editors of Spectroscopy regarding the "H-Classic Papers in Atomic Spectroscopy" article published in the November 2021 issue.
Latest:
Powerful Partners Provide Complete Analytical Solutions (PDF)This article examines advances that have been made to combine existing analytical techniques with Raman instrumentation. Some of these methods offer enhanced sample visualization, while others provide complementary vibrational spectroscopic information from a single sample point.
Latest:
Test of an In Vivo Method to Detect Chloroplast Division in Crop Plants, Part III: Statistical Proofs of Observation and General Utility of the Method (PDF)This article is the third installment in a series about a novel spectrofluorometric method that allow for in vivo observation of the division of chlorplast populations in leaves of Arabidopsis thalania.
Latest:
Simple and Effective Control of Spectral Overlap Interferences in ICP-MSThe authors discuss a new approach to the control of spectral overlap interferences in inductively coupled plasma–mass spectrometry.
Latest:
Transmission Raman Offers Improved Quantitation of Pharmaceutical SolidsManufacturing control of pharmaceutical solids requires routine measurement of content uniformity. Because of the high information content in Raman spectra, it has been considered a candidate technology for making these measurements.
Latest:
Tech Note: High-Resolution Ultrasonic Spectroscopy for Analysis of Chemical Reactions in Real Time (PDF)This article discusses direct real-time monitoring of chemical reactions, an important tool in industrial processes in industries such as chemical, biotechnology, food, and pharmaceutical.
Latest:
Determination of Recombinant Monoclonal Antibodies and Noncovalent Antigen TNFa Trimer Using Q-TOF Mass Spectrometry (PDF)This article discusses how quadrupole time-of-flight mass spectrometry was used to measure the intact molecular weights of large proteins and some noncovalent protein complexes.
Latest:
The Chemical Analysis ProcessThe authors present an overview of the chemical analysis process.
